Recombinant Mouse Endoplasmic reticulum aminopeptidase 1 (Erap1), partial, Mus musculus (Mouse), E.coli, N-terminal 10xHis-tagged and C-terminal Myc-tagged, 28.3kDa, purity >90% as determined by SDS-PAGE.
, ,

Recombinant Mouse Endoplasmic reticulum aminopeptidase 1 (Erap1), partial

Recombinant Mouse Endoplasmic reticulum aminopeptidase 1 (Erap1), partial — Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Purity >90%.

SKU: BCRECP-002654 Categories: , ,
Online Inquiry →

Product Specifications

Product SkuBCRECP-002654
Product DescriptionRecombinant Mouse Endoplasmic reticulum aminopeptidase 1 (Erap1) Protein is expressed from E.coli with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 731-930aa. [Accession | Q9EQH2].
Uniprot No.Q9EQH2
Gene NamesErap1
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region731-930aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight28.3kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasImmunology

Function

Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules.

Product Specifications

Recombinant Mouse Endoplasmic reticulum aminopeptidase 1 (Erap1), partial — Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Purity >90%. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney (By similarity)

Subcellular Location

Endoplasmic reticulum membrane (Single-pass type II membrane protein)

Subunit

Monomer. May also exist as a heterodimer; with ERAP2. Interacts with RBMX (By similarity)

Gene: Erap1  |  Organism: Mus musculus  |  Synonyms: ARTS-1; Adipocyte-derived leucine aminopeptidase; Aminopeptidase PILS; Puromycin-insensitive leucyl-specific aminopeptidase; VEGF-induced aminopeptidase

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

Shopping Cart
Scroll to Top