Recombinant Mouse Histone H2B type 1-M (Hist1h2bm), Mus musculus (Mouse), E.coli, N-terminal 6xHis-tagged, 17.8kDa, purity >90% as determined by SDS-PAGE.

Recombinant Mouse Histone H2B type 1-M (Hist1h2bm)

Recombinant Mouse Histone H2B type 1-M (Hist1h2bm) — Core component of nucleosome. Purity >90%.

SKU: BCRECP-002988 Category:
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Product Specifications

Product SkuBCRECP-002988
Product DescriptionRecombinant Mouse Histone H2B type 1-M (Hist1h2bm) Protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 2-126aa. [Accession | P10854].
Uniprot No.P10854
Gene NamesHist1h2bm
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region2-126aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 6xHis-tagged
Molecular weight17.8kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

Biological Context

Subcellular Location: Nucleus; Chromosome

Product Specifications

Recombinant Mouse Histone H2B type 1-M (Hist1h2bm) is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 2-126aa, with N-terminal 6xHis-tagged tag, molecular weight 17.8kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling

Subcellular Location

Nucleus; Chromosome

Subunit

The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA

Gene: H2bc14  |  Organism: Mus musculus  |  Synonyms: H2B 291B
Key Publications

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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