Recombinant Mouse Hyaluronan synthase 2 (Has2), partial, Mus musculus (Mouse), E.coli, N-terminal 6xHis-tagged, 39.9kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Mouse Hyaluronan synthase 2 (Has2), partial

Recombinant Mouse Hyaluronan synthase 2 (Has2), partial — Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Purity >90%.

SKU: BCRECP-002972 Categories: ,
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Product Specifications

Product SkuBCRECP-002972
Product DescriptionRecombinant Mouse Hyaluronan synthase 2 (Has2) Protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 67-374aa. [Accession | P70312].
Uniprot No.P70312
Gene NamesHas2
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region67-374aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 6xHis-tagged
Molecular weight39.9kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of three isoenzymes responsible for cellular hyaluronan synthesis and it is particularly responsible for the synthesis of high molecular mass hyaluronan.

Biological Context

Subcellular Location: Cell membrane (Multi-pass membrane protein); Endoplasmic reticulum membrane (Multi-pass membrane protein); Vesicle; Golgi apparatus membrane (Multi-pass membrane protein); Lysosome
Tissue Specificity: Expressed in heart, brain, spleen, lung and skeletal muscle
Pathway: Glycan biosynthesis; hyaluronan biosynthesis

Product Specifications

Recombinant Mouse Hyaluronan synthase 2 (Has2), partial is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 67-374aa, with N-terminal 6xHis-tagged tag, molecular weight 39.9kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation (By similarity). This is one of three isoenzymes responsible for cellular hyaluronan synthesis and it is particularly responsible for the synthesis of high molecular mass hyaluronan (PubMed:10455188)

Subcellular Location

Cell membrane (Multi-pass membrane protein); Endoplasmic reticulum membrane (Multi-pass membrane protein); Vesicle; Golgi apparatus membrane (Multi-pass membrane protein); Lysosome

Tissue Specificity

Expressed in heart, brain, spleen, lung and skeletal muscle

Subunit

Homodimer; dimerization promotes enzymatic activity. Forms heterodimer with HAS3. Forms heterodimer with HAS1

Pathway

Glycan biosynthesis; hyaluronan biosynthesis

Gene: Has2  |  Organism: Mus musculus  |  Synonyms: Hyaluronate synthase 2; Hyaluronic acid synthase 2
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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