Recombinant Mouse Hyaluronan synthase 2 (Has2), partial, Mus musculus (Mouse), E.coli, N-terminal 6xHis-tagged, 39.9kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Mouse Hyaluronan synthase 2 (Has2), partial

Recombinant Mouse Hyaluronan synthase 2 (Has2), partial — Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Purity >90%.

SKU: BCRECP-002972 Categories: ,
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Product Specifications

Product SkuBCRECP-002972
Product DescriptionRecombinant Mouse Hyaluronan synthase 2 (Has2) Protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 67-374aa. [Accession | P70312].
Uniprot No.P70312
Gene NamesHas2
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region67-374aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 6xHis-tagged
Molecular weight39.9kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of three isoenzymes responsible for cellular hyaluronan synthesis and it is particularly responsible for the synthesis of high molecular mass hyaluronan.

Biological Context

Subcellular Location: Cell membrane (Multi-pass membrane protein); Endoplasmic reticulum membrane (Multi-pass membrane protein); Vesicle; Golgi apparatus membrane (Multi-pass membrane protein); Lysosome
Tissue Specificity: Expressed in heart, brain, spleen, lung and skeletal muscle
Pathway: Glycan biosynthesis; hyaluronan biosynthesis

Product Specifications

Recombinant Mouse Hyaluronan synthase 2 (Has2), partial is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 67-374aa, with N-terminal 6xHis-tagged tag, molecular weight 39.9kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation (By similarity). This is one of three isoenzymes responsible for cellular hyaluronan synthesis and it is particularly responsible for the synthesis of high molecular mass hyaluronan (PubMed:10455188)

Subcellular Location

Cell membrane (Multi-pass membrane protein); Endoplasmic reticulum membrane (Multi-pass membrane protein); Vesicle; Golgi apparatus membrane (Multi-pass membrane protein); Lysosome

Tissue Specificity

Expressed in heart, brain, spleen, lung and skeletal muscle

Subunit

Homodimer; dimerization promotes enzymatic activity. Forms heterodimer with HAS3. Forms heterodimer with HAS1

Pathway

Glycan biosynthesis; hyaluronan biosynthesis

Gene: Has2  |  Organism: Mus musculus  |  Synonyms: Hyaluronate synthase 2; Hyaluronic acid synthase 2
Key Publications

Explore closely related product collections, technology platforms, and custom production resources.

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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