Recombinant Mouse Hydroxymethylglutaryl-CoA synthase, Cytoplasmic (Hmgcs1), Mus musculus (Mouse), E.coli, N-terminal 6xHis-SUMO-tagged, 73.6kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Mouse Hydroxymethylglutaryl-CoA synthase, Cytoplasmic (Hmgcs1)

Recombinant Mouse Hydroxymethylglutaryl-CoA synthase, Cytoplasmic (Hmgcs1) — recombinant protein from Mus musculus (Mouse), expressed in E.coli. Purity >90%.

SKU: BCRECP-002999 Categories: ,
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Product Specifications

Product SkuBCRECP-002999
Product DescriptionRecombinant Mouse Hydroxymethylglutaryl-CoA synthase, Cytoplasmic (Hmgcs1) Protein is expressed from E.coli with N-terminal 6xHis-SUMO-tagged. It contains 1-520aa. [Accession | Q8JZK9].
Uniprot No.Q8JZK9
Gene NamesHmgcs1
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-520aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 6xHis-SUMO-tagged
Molecular weight73.6kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate, a precursor for cholesterol synthesis.

Biological Context

Subcellular Location: Cytoplasm
Pathway: Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 2/3

Product Specifications

Recombinant Mouse Hydroxymethylglutaryl-CoA synthase, Cytoplasmic (Hmgcs1) is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 1-520aa, with N-terminal 6xHis-SUMO-tagged tag, molecular weight 73.6kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate, a precursor for cholesterol synthesis

Subcellular Location

Cytoplasm

Subunit

Homodimer

Pathway

Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 2/3

Gene: Hmgcs1  |  Organism: Mus musculus  |  Synonyms: 3-hydroxy-3-methylglutaryl coenzyme A synthase

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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