Recombinant Mouse Hydroxymethylglutaryl-CoA synthase, mitochondrial (Hmgcs2), Mus musculus (Mouse), Yeast, C-terminal 6xHis-tagged, 53.6kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Mouse Hydroxymethylglutaryl-CoA synthase, mitochondrial (Hmgcs2)

Recombinant Mouse Hydroxymethylglutaryl-CoA synthase, mitochondrial (Hmgcs2) — recombinant protein from Mus musculus (Mouse), expressed in Yeast. Purity >90%.

SKU: BCRECP-003001 Categories: ,
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Product Specifications

Product SkuBCRECP-003001
Product DescriptionRecombinant Mouse Hydroxymethylglutaryl-CoA synthase, mitochondrial (Hmgcs2) Protein is expressed from Yeast with C-terminal 6xHis-tagged. It contains 38-508aa. [Accession | P54869].
Uniprot No.P54869
Gene NamesHmgcs2
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemYeast
Expression Region38-508aa
SpeciesMus musculus (Mouse)
Tag InfoC-terminal 6xHis-tagged
Molecular weight53.6kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCancer

Function

Catalyzes the first irreversible step in ketogenesis, condensing acetyl-CoA to acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate.

Biological Context

Subcellular Location: Mitochondrion
Tissue Specificity: Liver and kidney
Pathway: Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 2/3

Product Specifications

Recombinant Mouse Hydroxymethylglutaryl-CoA synthase, mitochondrial (Hmgcs2) is a recombinant protein from Mus musculus (Mouse), expressed in Yeast, covering amino acids 38-508aa, with C-terminal 6xHis-tagged tag, molecular weight 53.6kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

Catalyzes the first irreversible step in ketogenesis, condensing acetyl-CoA to acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate

Subcellular Location

Mitochondrion

Tissue Specificity

Liver and kidney

Subunit

Homodimer

Pathway

Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 2/3

Gene: Hmgcs2  |  Organism: Mus musculus  |  Synonyms: 3-hydroxy-3-methylglutaryl coenzyme A synthase
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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