Recombinant Mouse Immunoglobulin J chain (Jchain), Mus musculus (Mouse), E.coli, N-terminal 6xHis-SUMO-tagged, 31.7kDa, purity >90% as determined by SDS-PAGE.

Recombinant Mouse Immunoglobulin J chain (Jchain)

Recombinant Mouse Immunoglobulin J chain (Jchain) — Serves to link two monomer units of either IgM or IgA. Purity >90%.

SKU: BCRECP-003203 Category:
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Product Specifications

Product SkuBCRECP-003203
Product DescriptionRecombinant Mouse Immunoglobulin J chain (Jchain) Protein is expressed from E.coli with N-terminal 6xHis-SUMO-tagged. It contains 22-159aa. [Accession | P01592].
Uniprot No.P01592
Gene NamesJchain
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region22-159aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 6xHis-SUMO-tagged
Molecular weight31.7kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasImmunology

Function

Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces dimers and/or larger polymers. It also helps to bind these immunoglobulins to secretory component.

Biological Context

Subcellular Location: Secreted

Product Specifications

Recombinant Mouse Immunoglobulin J chain (Jchain) is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 22-159aa, with N-terminal 6xHis-SUMO-tagged tag, molecular weight 31.7kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces dimers and/or larger polymers. It also helps to bind these immunoglobulins to secretory component

Subcellular Location

Secreted

Subunit

Part of the secretory IgA (sIgA) complex that consists of two, four or five IgA monomers, and two additional non-Ig polypeptides, namely the JCHAIN and the secretory component (the proteolytic product of PIGR). Part of the secretory IgM (sIgM) complex that consist of five IgM monomers, and two additional non-Ig polypeptides, namely the JCHAIN and the secretory component (the proteolytic product of PIGR). JCHAIN-containing IgM interacts (via CH4 domain) with FCRM (via Ig-like domain)

Gene: Jchain  |  Organism: Mus musculus

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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