Recombinant Mouse Interleukin-1 receptor antagonist protein (Il1rn), Mus musculus (Mouse), E.Coli, Tag-Free, 17.3 kDa, purity >>97% as determined by SDS-PAGE.
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Recombinant Mouse Interleukin-1 receptor antagonist protein (Il1rn)

Recombinant Mouse Interleukin-1 receptor antagonist protein (Il1rn) — Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Purity >97%.

SKU: BCACP-000711 Categories: ,
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Product SKUBCACP-000711
Product DescriptionRecombinant Mouse Interleukin-1 receptor antagonist protein (Il1rn) protein is expressed from E.Coli with Tag-Free. It contains 27-178aa. [Accession | P25085].
Uniprot No.P25085
Gene NamesIl1rn
Purity>97% as determined by SDS-PAGE.
Expression SystemE.Coli
Expression Region27-178aa
SpeciesMus musculus (Mouse)
Tag InfoTag-Free
Molecular weight17.3 kDa
ActivityFully biologically active when compared to standard. The ED50 as determined by the dose-dependant prolifiration of Murine HT-2 cells is less then 2 ng/ml, corresponding to a Specific Activity of >5x105 IU/mg.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesIl1rn; Il-1raInterleukin-1 receptor antagonist protein; IL-1RN; IL-1ra; IRAP; IL1 inhibitor

Function

Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.

Biological Context

Subcellular Location: Cytoplasm

Product Specifications

Recombinant Mouse Interleukin-1 receptor antagonist protein (Il1rn) is a recombinant protein from Mus musculus (Mouse), expressed in E.Coli, covering amino acids 27-178aa, with Tag-Free tag, molecular weight 17.3 kDa, purity >97% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens

Subcellular Location

Cytoplasm

Gene: Il1rn  |  Organism: Mus musculus  |  Synonyms: IL1 inhibitor
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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