Recombinant Mouse Kielin/chordin-like protein (Kcp), partial

Recombinant Mouse Kielin/chordin-like protein (Kcp), partial — Enhances bone morphogenetic protein (BMP) signaling in a paracrine manner. Purity >85%.

SKU: BCRECP-003208 Category:

Product Specifications

Product SkuBCRECP-003208
Product DescriptionRecombinant Mouse Kielin/chordin-like protein (Kcp) Protein is expressed from E.coli with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 1085-1425aa. [Accession | Q3U492].
Uniprot No.Q3U492
Gene NamesKcp
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1085-1425aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight44.7kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCell Biology

Function

Enhances bone morphogenetic protein (BMP) signaling in a paracrine manner. In contrast, it inhibits both the activin-A and TGFB1-mediated signaling pathways.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Weakly expressed in embryonic kidney and brain. Not expressed in adult tissues and several cell lines

Product Specifications

Recombinant Mouse Kielin/chordin-like protein (Kcp), partial is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 1085-1425aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 44.7kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Enhances bone morphogenetic protein (BMP) signaling in a paracrine manner. In contrast, it inhibits both the activin-A and TGFB1-mediated signaling pathways

Subcellular Location

Secreted

Tissue Specificity

Weakly expressed in embryonic kidney and brain. Not expressed in adult tissues and several cell lines

Subunit

Interacts with BMP7 and, by doing so, enhances binding to the type I receptors that contains cytoplasmic serine-/threonine protein kinase domains. Also able to interact with activin-A and TGFB1

Gene: Kcp  |  Organism: Mus musculus  |  Synonyms: Cysteine-rich BMP regulator 2; Cysteine-rich motor neuron 2 protein; Kielin/chordin-like protein 1

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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