Recombinant Mouse Kielin/chordin-like protein (Kcp), partial, Mus musculus (Mouse), E.coli, N-terminal 10xHis-tagged and C-terminal Myc-tagged, 44.7kDa, purity >85% as determined by SDS-PAGE.

Recombinant Mouse Kielin/chordin-like protein (Kcp), partial

Recombinant Mouse Kielin/chordin-like protein (Kcp), partial — Enhances bone morphogenetic protein (BMP) signaling in a paracrine manner. Purity >85%.

SKU: BCRECP-003208 Category:
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Product Specifications

Product SkuBCRECP-003208
Product DescriptionRecombinant Mouse Kielin/chordin-like protein (Kcp) Protein is expressed from E.coli with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 1085-1425aa. [Accession | Q3U492].
Uniprot No.Q3U492
Gene NamesKcp
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1085-1425aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight44.7kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCell Biology

Function

Enhances bone morphogenetic protein (BMP) signaling in a paracrine manner. In contrast, it inhibits both the activin-A and TGFB1-mediated signaling pathways.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Weakly expressed in embryonic kidney and brain. Not expressed in adult tissues and several cell lines

Product Specifications

Recombinant Mouse Kielin/chordin-like protein (Kcp), partial is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 1085-1425aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 44.7kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Enhances bone morphogenetic protein (BMP) signaling in a paracrine manner. In contrast, it inhibits both the activin-A and TGFB1-mediated signaling pathways

Subcellular Location

Secreted

Tissue Specificity

Weakly expressed in embryonic kidney and brain. Not expressed in adult tissues and several cell lines

Subunit

Interacts with BMP7 and, by doing so, enhances binding to the type I receptors that contains cytoplasmic serine-/threonine protein kinase domains. Also able to interact with activin-A and TGFB1

Gene: Kcp  |  Organism: Mus musculus  |  Synonyms: Cysteine-rich BMP regulator 2; Cysteine-rich motor neuron 2 protein; Kielin/chordin-like protein 1

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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