Recombinant Mouse Lymphocyte activation gene 3 protein (Lag3), partial, Mus musculus (Mouse), Mammalian cell, C-terminal 10xHis-tagged, 46.6kDa, purity >95% as determined by SDS-PAGE.

Recombinant Mouse Lymphocyte activation gene 3 protein (Lag3), partial

Recombinant Mouse Lymphocyte activation gene 3 protein (Lag3), partial — recombinant protein from Mus musculus (Mouse), expressed in Mammalian cell. Purity >95%.

SKU: BCRECP-003237 Category:
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Product Specifications

Product SkuBCRECP-003237
Product DescriptionRecombinant Mouse Lymphocyte activation gene 3 protein (Lag3) Protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 24-442aa. [Accession | Q61790].
Uniprot No.Q61790
Gene NamesLag3
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region24-442aa
SpeciesMus musculus (Mouse)
Tag InfoC-terminal 10xHis-tagged
Molecular weight46.6kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasImmunology

Function

May function as a ligand for MHC class II (MHC-II) on antigen-presenting cells (APC), promoting APC activation/maturation and driving Th1 immune response.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Primarily expressed in activated CD4(+) and CD8(+) T-cells. Also expressed in a subset of regulatory T-cells (Tregs), such as natural CD4(+)CD25(+) Tregs. Also expressed on plasmacytoid dendritic cells (pDCs)

Product Specifications

Recombinant Mouse Lymphocyte activation gene 3 protein (Lag3), partial is a recombinant protein from Mus musculus (Mouse), expressed in Mammalian cell, covering amino acids 24-442aa, with C-terminal 10xHis-tagged tag, molecular weight 46.6kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

May function as a ligand for MHC class II (MHC-II) on antigen-presenting cells (APC), promoting APC activation/maturation and driving Th1 immune response

Subcellular Location

Secreted

Tissue Specificity

Primarily expressed in activated CD4(+) and CD8(+) T-cells (PubMed:12209638). Also expressed in a subset of regulatory T-cells (Tregs), such as natural CD4(+)CD25(+) Tregs (PubMed:15485628). Also expressed on plasmacytoid dendritic cells (pDCs) (PubMed:19201841)

Subunit

Homodimer (PubMed:35761082, PubMed:38483996, PubMed:39209860). Interacts with CD3E; disrupting the association between CD3E and LCK, thereby preventing TCR activation (PubMed:40592325)

Gene: Lag3  |  Organism: Mus musculus  |  Synonyms: Activation-induced cytidine deaminase-linked autoimmunity protein
Key Publications

Explore closely related product collections, technology platforms, and custom production resources.

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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