Recombinant Mouse Neutrophilic granule protein (Ngp), Mus musculus (Mouse), E.coli, N-terminal 10xHis-tagged, 23.2kDa, purity >95% as determined by SDS-PAGE.

Recombinant Mouse Neutrophilic granule protein (Ngp)

Recombinant Mouse Neutrophilic granule protein (Ngp) — Acts as an inhibitor of cathepsin B (CTSB) activity. Purity >95%.

SKU: BCRECP-003871 Category:
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Product Specifications

Product SkuBCRECP-003871
Product DescriptionRecombinant Mouse Neutrophilic granule protein (Ngp) Protein is expressed from E.coli with N-terminal 10xHis-tagged. It contains 22-167aa. [Accession | O08692].
Uniprot No.O08692
Gene NamesNgp
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region22-167aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 10xHis-tagged
Molecular weight23.2kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Acts as an inhibitor of cathepsin B (CTSB) activity. Plays a role as a negative regulator of tumor vascular development, cell invasion and metastasis.

Biological Context

Subcellular Location: Secreted; Cytoplasmic granule
Tissue Specificity: Expressed in myeloid bone marrow cells. Expressed in neutrophilic precursors (at protein level). Expressed in myeloid bone marrow cells

Product Specifications

Recombinant Mouse Neutrophilic granule protein (Ngp) is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 22-167aa, with N-terminal 10xHis-tagged tag, molecular weight 23.2kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Acts as an inhibitor of cathepsin B (CTSB) activity. Plays a role as a negative regulator of tumor vascular development, cell invasion and metastasis

Subcellular Location

Secreted; Cytoplasmic granule

Tissue Specificity

Expressed in myeloid bone marrow cells. Expressed in neutrophilic precursors (at protein level) (PubMed:8749713). Expressed in myeloid bone marrow cells (PubMed:21518852)

Subunit

Monomer. Homodimer; disulfide-linked

Gene: Ngp  |  Organism: Mus musculus  |  Synonyms: Cystatin-like protein; Myeloid bactenecin protein; Myeloid secondary granule protein
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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