Recombinant Mouse Nicotinamide phosphoribosyltransferase (Nampt) (C39S), Mus musculus (Mouse), E.coli, N-terminal 6xHis-tagged and C-terminal HA-tagged, 60.6kDa, purity >90% as determined by SDS-PAGE.
,

Recombinant Mouse Nicotinamide phosphoribosyltransferase (Nampt) (C39S)

Recombinant Mouse Nicotinamide phosphoribosyltransferase (Nampt) (C39S) — The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by A… Purity >90%.

SKU: BCRECP-003844 Categories: ,
Online Inquiry →

Product Specifications

Product SkuBCRECP-003844
Product DescriptionRecombinant Mouse Nicotinamide phosphoribosyltransferase (Nampt) (C39S) Protein is expressed from E.coli with N-terminal 6xHis-tagged and C-terminal HA-tagged. It contains 1-491aa(C39S). [Accession | Q99KQ4].
Uniprot No.Q99KQ4
Gene NamesNampt
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-491aa(C39S)
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 6xHis-tagged and C-terminal HA-tagged
Molecular weight60.6kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasBiochemicals

Function

The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway.

Biological Context

Subcellular Location: Nucleus; Cytoplasm; Secreted
Tissue Specificity: Ubiquitously expressed in lymphoid and non-lymphoid tissues
Pathway: Cofactor biosynthesis; NAD(+) biosynthesis; nicotinamide D-ribonucleotide from 5-phospho-alpha-D-ribose 1-diphosphate and nicotinamide: step 1/1

Product Specifications

Recombinant Mouse Nicotinamide phosphoribosyltransferase (Nampt) (C39S) is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 1-491aa(C39S), with N-terminal 6xHis-tagged and C-terminal HA-tagged tag, molecular weight 60.6kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma (By similarity). Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression

Subcellular Location

Nucleus; Cytoplasm; Secreted

Tissue Specificity

Ubiquitously expressed in lymphoid and non-lymphoid tissues

Subunit

Homodimer

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinamide D-ribonucleotide from 5-phospho-alpha-D-ribose 1-diphosphate and nicotinamide: step 1/1

Gene: Nampt  |  Organism: Mus musculus  |  Synonyms: Pre-B-cell colony-enhancing factor 1 homolog; Visfatin
Key Publications

Explore closely related product collections, technology platforms, and custom production resources.

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

Shopping Cart
Scroll to Top