Recombinant Mouse Peroxisomal coenzyme A diphosphatase NUDT7 (Nudt7), Mus musculus (Mouse), E.coli, C-terminal 6xHis-tagged, 33.9kDa, purity >85% as determined by SDS-PAGE.
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Recombinant Mouse Peroxisomal coenzyme A diphosphatase NUDT7 (Nudt7)

Recombinant Mouse Peroxisomal coenzyme A diphosphatase NUDT7 (Nudt7) — Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4′-phosphopantetheine and adenosine 3′,5′-bisphosphate. Purity >85%.

SKU: BCRECP-003918 Categories: ,
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Product Specifications

Product SkuBCRECP-003918
Product DescriptionRecombinant Mouse Peroxisomal coenzyme A diphosphatase NUDT7 (Nudt7) Protein is expressed from E.coli with C-terminal 6xHis-tagged. It contains 1-236aa. [Accession | Q99P30].
Uniprot No.Q99P30
Gene NamesNudt7
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-236aa
SpeciesMus musculus (Mouse)
Tag InfoC-terminal 6xHis-tagged
Molecular weight33.9kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasEpigenetics and Nuclear Signaling

Function

Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Cleaves CoA, CoA esters and oxidized CoA with similar efficiencies. Preferentially hydrolyzes medium-chain acyl-CoAs and bile acid-CoAs.

Biological Context

Subcellular Location: Peroxisome
Tissue Specificity: Expressed in liver, brown adipose tissue and heart at 20 times lower levels than isoform 1

Product Specifications

Recombinant Mouse Peroxisomal coenzyme A diphosphatase NUDT7 (Nudt7) is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 1-236aa, with C-terminal 6xHis-tagged tag, molecular weight 33.9kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate (PubMed:11415433, PubMed:18799520, PubMed:29378847). Cleaves CoA, CoA esters and oxidized CoA with similar efficiencies (PubMed:11415433). Preferentially hydrolyzes medium-chain acyl-CoAs and bile acid-CoAs (PubMed:18799520). Has no activity toward NDP-sugars, CDP-alcohols, (deoxy)nucleoside 5'-triphosphates, nucleoside 5'-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or thymidine-5'-monophospho-p-nitrophenyl ester (PubMed:18799520). May be required to eliminate oxidized CoA from peroxisomes, or regulate CoA and acyl-CoA levels in this organelle in response to metabolic demand (PubMed:18799520). Does not play a role in U8 snoRNA decapping activity (PubMed:21070968). Binds U8 snoRNA (PubMed:21070968). Exhibits decapping activity towards dpCoA-capped RNAs in vitro (PubMed:32432673)

Subcellular Location

Peroxisome

Tissue Specificity

Expressed in liver, brown adipose tissue and heart at 20 times lower levels than isoform 1

Subunit

Monomer

Gene: Nudt7  |  Organism: Mus musculus  |  Synonyms: Nucleoside diphosphate-linked moiety X motif 7
Key Publications

Explore closely related product collections, technology platforms, and custom production resources.

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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