Recombinant Mouse Pro-neuropeptide Y (Npy), partial

Recombinant Mouse Pro-neuropeptide Y (Npy), partial — Ligand for neuropeptide Y receptor type 1 (NPY1R) and neuropeptide Y receptor type 2 (NPY2R). Purity >90%.

SKU: BCRECP-003903 Category:

Product Specifications

Product SkuBCRECP-003903
Product DescriptionRecombinant Mouse Pro-neuropeptide Y (Npy) Protein is expressed from Yeast with N-terminal hFc-tagged. It contains 29-64aa. [Accession | P57774].
Uniprot No.P57774
Gene NamesNpy
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemYeast
Expression Region29-64aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal hFc-tagged
Molecular weight30.9kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasNeuroscience

Function

Ligand for neuropeptide Y receptor type 1 (NPY1R) and neuropeptide Y receptor type 2 (NPY2R). Receptor binding induces adenylate cyclase-inhibiting G protein-coupled receptor signaling, resulting in inhibition of cAMP production. Receptor activation by NPY also leads to an increase of intracellular Ca(2+) levels.

Biological Context

Subcellular Location: Secreted; Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle
Tissue Specificity: One of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla

Product Specifications

Recombinant Mouse Pro-neuropeptide Y (Npy), partial is a recombinant protein from Mus musculus (Mouse), expressed in Yeast, covering amino acids 29-64aa, with N-terminal hFc-tagged tag, molecular weight 30.9kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Ligand for neuropeptide Y receptor type 1 (NPY1R) and neuropeptide Y receptor type 2 (NPY2R). Receptor binding induces adenylate cyclase-inhibiting G protein-coupled receptor signaling, resulting in inhibition of cAMP production. Receptor activation by NPY also leads to an increase of intracellular Ca(2+) levels. Is involved in the regulation of eating behaviour, acting as a stimulator of food intake (By similarity). Involved in the regulation of colonic antisecretory tone, and colonic contractility (PubMed:21457230)

Subcellular Location

Secreted; Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle

Tissue Specificity

One of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla

Gene: Npy  |  Organism: Mus musculus
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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