Recombinant Mouse Prohibitin (Phb), partial, Mus musculus (Mouse), E.coli, N-terminal 10xHis-tagged, 16.2kDa, purity >85% as determined by SDS-PAGE.

Recombinant Mouse Prohibitin (Phb), partial

Recombinant Mouse Prohibitin (Phb), partial — (Microbial infection) In neuronal cells, cell surface-expressed PHB1 is involved in human enterovirus 71/EV-71 entry into neuronal cells specifically, while membrane-bound mitochondrial PHB1 associ… Purity >85%.

SKU: BCRECP-004067 Category:
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Product Specifications

Product SkuBCRECP-004067
Product DescriptionRecombinant Mouse Prohibitin (Phb) Protein is expressed from E.coli with N-terminal 10xHis-tagged. It contains 174-272aa. [Accession | P67778].
Uniprot No.P67778
Gene NamesPhb
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region174-272aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 10xHis-tagged
Molecular weight16.2kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasTranscription

Function

(Microbial infection) In neuronal cells, cell surface-expressed PHB1 is involved in human enterovirus 71/EV-71 entry into neuronal cells specifically, while membrane-bound mitochondrial PHB1 associates with the virus replication complex and facilitates viral replication. May serve as a receptor for EV71.

Biological Context

Subcellular Location: Mitochondrion inner membrane; Nucleus; Cell membrane; Cytoplasm
Tissue Specificity: Widely expressed in different tissues

Product Specifications

Recombinant Mouse Prohibitin (Phb), partial is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 174-272aa, with N-terminal 10xHis-tagged tag, molecular weight 16.2kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

(Microbial infection) In neuronal cells, cell surface-expressed PHB1 is involved in human enterovirus 71/EV-71 entry into neuronal cells specifically, while membrane-bound mitochondrial PHB1 associates with the virus replication complex and facilitates viral replication (PubMed:29324904). May serve as a receptor for EV71 (PubMed:29324904)

Subcellular Location

Mitochondrion inner membrane; Nucleus; Cell membrane; Cytoplasm

Tissue Specificity

Widely expressed in different tissues

Subunit

(Microbial infection) Interacts with human enterovirus 71/EV-71 capsid protein VP0, protein 3CD and protease 3C

Gene: Phb1  |  Organism: Mus musculus  |  Synonyms: B-cell receptor-associated protein 32
Key Publications

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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