Recombinant Mouse Properdin (Cfp), Mus musculus (Mouse), Mammalian cell, N-terminal 10xHis-tagged and C-terminal Myc-tagged, 53kDa, purity >85% as determined by SDS-PAGE.

Recombinant Mouse Properdin (Cfp)

Recombinant Mouse Properdin (Cfp) — A positive regulator of the alternate pathway of complement. Purity >85%.

SKU: BCRECP-004174 Category:
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Product Specifications

Product SkuBCRECP-004174
Product DescriptionRecombinant Mouse Properdin (Cfp) Protein is expressed from Mammalian cell with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 23-464aa. [Accession | P11680].
Uniprot No.P11680
Gene NamesProperdin
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region23-464aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight53kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasImmunology

Function

A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Inhibits CFI-CFH mediated degradation of Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b).

Biological Context

Subcellular Location: Secreted

Product Specifications

Recombinant Mouse Properdin (Cfp) is a recombinant protein from Mus musculus (Mouse), expressed in Mammalian cell, covering amino acids 23-464aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 53kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

A positive regulator of the alternate pathway of complement (PubMed:28264884). It binds to and stabilizes the C3- and C5-convertase enzyme complexes (By similarity). Inhibits CFI-CFH mediated degradation of Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b) (By similarity)

Subcellular Location

Secreted

Subunit

In plasma, properdin exists as dimers, trimers or tetramers in the relative proportions of 26:54:20 (By similarity). Interacts with the pro-C3-convertase enzyme complex (C3b-Bb) comprised of Complement C3 beta chain (C3b) and the Complement factor B Bb fragment (Bb), where it binds (via its TSP type-1 5 domain) with C3b and Bb (By similarity). This interaction stabilizes the complex and allows it to become the active C3-convertase enzyme complex (C3b-Bb-FP) (By similarity). Interacts with C3b (PubMed:28264884). Interacts with CFB (By similarity)

Gene: Cfp  |  Organism: Mus musculus  |  Synonyms: Complement factor P

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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