Recombinant Mouse Regenerating islet-derived protein 3-beta (Reg3b), Mus musculus (Mouse), E.coli, Tag-Free, 15.6kDa, purity >95% as determined by SDS-PAGE.

Recombinant Mouse Regenerating islet-derived protein 3-beta (Reg3b)

Recombinant Mouse Regenerating islet-derived protein 3-beta (Reg3b) — Acts as a hormone in response to different stimuli. Purity >95%.

SKU: BCRECP-004249 Category:
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Product Specifications

Product SkuBCRECP-004249
Product DescriptionRecombinant Mouse Regenerating islet-derived protein 3-beta (Reg3b) Protein is expressed from E.coli with Tag-Free. It contains 38-175aa. [Accession | P35230].
Uniprot No.P35230
Gene NamesReg3b
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region38-175aa
SpeciesMus musculus (Mouse)
Tag InfoTag-Free
Molecular weight15.6kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Acts as a hormone in response to different stimuli. Secreted by different cell types to activate its receptor EXTL3 and induce cell specific signaling pathways. In pancreas, is able stimulate cell proliferation.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Constitutively expressed in the small intestine, moderately in colon and at an extremely low level in healthy pancreas
Disease Association: [Overexpressed during the acute phase of pancreatitis]

Product Specifications

Recombinant Mouse Regenerating islet-derived protein 3-beta (Reg3b) is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 38-175aa, with Tag-Free tag, molecular weight 15.6kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Acts as a hormone in response to different stimuli. Secreted by different cell types to activate its receptor EXTL3 and induce cell specific signaling pathways (PubMed:34099862). In pancreas, is able stimulate cell proliferation (PubMed:34099862)

Subcellular Location

Secreted

Disease Association

[Overexpressed during the acute phase of pancreatitis]

Tissue Specificity

Constitutively expressed in the small intestine, moderately in colon and at an extremely low level in healthy pancreas

Subunit

Forms a hexameric membrane-permeabilizing oligomeric pore on membrane phospholipids. The hexamer is formed by three dimers related by helical symmetry. Forms filaments, filamentation traps pore complexes and limits damage to host cells. Interacts with EXTL3

Gene: Reg3b  |  Organism: Mus musculus  |  Synonyms: Pancreatitis-associated protein 1; Regenerating islet-derived protein III-beta
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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