Recombinant Mouse Transcription factor A, mitochondrial (Tfam), Mus musculus (Mouse), E.coli, N-terminal 10xHis-tagged and C-terminal Myc-tagged, 30.9kDa, purity >90% as determined by SDS-PAGE.

Recombinant Mouse Transcription factor A, mitochondrial (Tfam)

Recombinant Mouse Transcription factor A, mitochondrial (Tfam) — recombinant protein from Mus musculus (Mouse), expressed in E.coli. Purity >90%.

SKU: BCRECP-004544 Category:
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Product Specifications

Product SkuBCRECP-004544
Product DescriptionRecombinant Mouse Transcription factor A, mitochondrial (Tfam) Protein is expressed from E.coli with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 43-243aa. [Accession | P40630].
Uniprot No.P40630
Gene NamesTfam
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region43-243aa
SpeciesMus musculus (Mouse)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight30.9kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCardiovascular

Function

May also function as a transcriptional activator or may have a structural role in the compaction of nuclear DNA during spermatogenesis.

Biological Context

Subcellular Location: Nucleus
Tissue Specificity: The mitochondrial isoform is widely expressed while the nuclear isoform is testis-specific

Product Specifications

Recombinant Mouse Transcription factor A, mitochondrial (Tfam) is a recombinant protein from Mus musculus (Mouse), expressed in E.coli, covering amino acids 43-243aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 30.9kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

May also function as a transcriptional activator or may have a structural role in the compaction of nuclear DNA during spermatogenesis

Subcellular Location

Nucleus

Tissue Specificity

The mitochondrial isoform is widely expressed while the nuclear isoform is testis-specific

Subunit

Monomer; binds DNA as a monomer. Homodimer. Component of the mitochondrial transcription initiation complex, composed at least of TFB2M, TFAM and POLRMT. In this complex TFAM recruits POLRMT to the promoter whereas TFB2M induces structural changes in POLRMT to enable promoter opening and trapping of the DNA non-template strand. Upon metabolic stress, forms a complex composed of FOXO3, SIRT3, TFAM and POLRMT. Interacts with TFB1M and TFB2M. Interacts with CLPX; this enhances DNA-binding

Gene: Tfam  |  Organism: Mus musculus  |  Synonyms: Testis-specific high mobility group protein
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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