Recombinant Mouse Tumor necrosis factor receptor superfamily member 5 (Cd40), partial (Active), Mus musculus (Mouse), Mammalian cell, C-terminal hFc-tagged, 46.8 kDa, purity >95% as determined by SDS-PAGE.
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Recombinant Mouse Tumor necrosis factor receptor superfamily member 5 (Cd40), partial (Active)

Recombinant Mouse Tumor necrosis factor receptor superfamily member 5 (Cd40), partial (Active) — Receptor for TNFSF5/CD40LG. Purity >95%.

SKU: BCACP-000525 Categories: , ,
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Product SKUBCACP-000525
Product DescriptionRecombinant Mouse Tumor necrosis factor receptor superfamily member 5 (Cd40) protein is expressed from Mammalian cell with C-terminal hFc-tagged. It contains 20-193aa. [Accession | P27512].
Uniprot No.P27512
Gene NamesCd40
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region20-193aa
SpeciesMus musculus (Mouse)
Tag InfoC-terminal hFc-tagged
Molecular weight46.8 kDa
ActivityMeasured in a cytotoxicity assay using L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is 17.58-26.84 pg/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesTumor necrosis factor receptor superfamily member 5; B-cell surface antigen CD40; Bp50; CD40L receptor; CD40; Cd40; Tnfrsf5

Function

Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.

Product Specifications

Recombinant Mouse Tumor necrosis factor receptor superfamily member 5 (Cd40), partial (Active) is a recombinant protein, expressed in Mammalian cell, covering amino acids 20-193aa, with C-terminal hFc-tagged tag, molecular weight 46.8 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured in a cytotoxicity assay using L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is 17.58-26.84 pg/mL.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (PubMed:12881420)

Gene: Cd40  |  Organism: Mus musculus

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Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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