Function
Shows cytolytic activity on many different cells by forming pore in lipid membranes. In vivo, increases heart rate or kills the animal by cardiac arrest. In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity.
Product Specifications
Recombinant Naja sputatrix Cytotoxin 1 is a recombinant protein, expressed in E.coli, covering amino acids 22-81aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 14.2kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.
