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Recombinant Newcastle disease virus Hemagglutinin-neuraminidase (HN) Protein

Recombinant Newcastle disease virus Hemagglutinin-neuraminidase (HN) Protein — recombinant protein from Newcastle disease virus (strain Her/33) (NDV), expressed in in vitro E.coli expression system. Purity >85%.

SKU: BCRECP-00138TM Categories: ,

Product Specifications

Uniprot No.P35741
Gene NamesHN
PurityGreater than 85% as determined by SDS-PAGE.
Expression Systemin vitro E.coli expression system
Expression Region1-571aa
SpeciesNewcastle disease virus (strain Her/33) (NDV)
Tag InfoN-terminal 10xHis-tagged
Molecular weight68.7kDa
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Function

Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins.

Biological Context

Subcellular Location: Virion membrane (Single-pass type II membrane protein); Host cell membrane (Single-pass type II membrane protein)

Product Specifications

Recombinant Newcastle disease virus Hemagglutinin-neuraminidase (HN) Protein is a recombinant protein from Newcastle disease virus (strain Her/33) (NDV), expressed in in vitro E.coli expression system, covering amino acids 1-571aa, with N-terminal 10xHis-tagged tag, molecular weight 68.7kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Not implied unless activity data are explicitly listed on this product page, the datasheet, or the CoA.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins

Subcellular Location

Virion membrane (Single-pass type II membrane protein); Host cell membrane (Single-pass type II membrane protein)

Subunit

Homotetramer; composed of disulfide-linked homodimers (By similarity). Interacts with F protein trimer (By similarity). Interacts with host CG-1B; this interaction inhibits viral adsorption and replication rather than internalization (By similarity)

Gene: HN  |  Organism: Newcastle disease virus (strain Her/33)

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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