Recombinant Pan troglodytes Histone demethylase UTY (UTY), partial

Recombinant Pan troglodytes Histone demethylase UTY (UTY), partial — Male-specific histone demethylase that catalyzes trimethylated ‘Lys-27’ (H3K27me3) demethylation in histone H3. Purity >85%.

SKU: BCRECP-004696 Category:

Product Specifications

Product SkuBCRECP-004696
Product DescriptionRecombinant Pan troglodytes Histone demethylase UTY (UTY) Protein is expressed from E.coli with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 209-317aa. [Accession | Q6B4Z3].
Uniprot No.Q6B4Z3
Gene NamesUTY
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region209-317aa
SpeciesPan troglodytes (Chimpanzee)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight19.9kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasEpigenetics and Nuclear Signaling

Function

Male-specific histone demethylase that catalyzes trimethylated 'Lys-27' (H3K27me3) demethylation in histone H3. Has relatively low lysine demethylase activity.

Biological Context

Subcellular Location: Nucleus

Product Specifications

Recombinant Pan troglodytes Histone demethylase UTY (UTY), partial is a recombinant protein from Pan troglodytes (Chimpanzee), expressed in E.coli, covering amino acids 209-317aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 19.9kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Male-specific histone demethylase that catalyzes trimethylated 'Lys-27' (H3K27me3) demethylation in histone H3. Has relatively low lysine demethylase activity

Subcellular Location

Nucleus

Subunit

Interacts with TLE1 and TLE2

Gene: UTY  |  Organism: Pan troglodytes  |  Synonyms: Ubiquitously transcribed TPR protein on the Y chromosome; Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein; [histone H3]-trimethyl-L-lysine(27) demethylase UTY

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What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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