Recombinant Pig Interleukin-5 (IL5), Sus scrofa (Pig), E.coli, N-terminal 6xHis-tagged, 17.0kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Pig Interleukin-5 (IL5)

Recombinant Pig Interleukin-5 (IL5) — Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Purity >90%.

SKU: BCRECP-003164 Categories: ,
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Product Specifications

Product SkuBCRECP-003164
Product DescriptionRecombinant Pig Interleukin-5 (IL5) Protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 22-134aa. [Accession | Q9MYM5].
Uniprot No.Q9MYM5
Gene NamesIL5
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region22-134aa
SpeciesSus scrofa (Pig)
Tag InfoN-terminal 6xHis-tagged
Molecular weight17.0kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasImmunology

Function

Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Also acts on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation. Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB.

Biological Context

Subcellular Location: Secreted

Product Specifications

Recombinant Pig Interleukin-5 (IL5) is a recombinant protein from Sus scrofa (Pig), expressed in E.coli, covering amino acids 22-134aa, with N-terminal 6xHis-tagged tag, molecular weight 17.0kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Also acts on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation (By similarity). Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively (By similarity)

Subcellular Location

Secreted

Subunit

Homodimer; disulfide-linked. Interacts with IL5RA. Interacts with CSF2RB

Gene: IL5  |  Organism: Sus scrofa  |  Synonyms: Eosinophil differentiation factor; T-cell replacing factor

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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