Recombinant Pig Leukocyte elastase inhibitor (SERPINB1), Sus scrofa (Pig), E.coli, N-terminal 10xHis-tagged and C-terminal Myc-tagged, 50.0kDa, purity >85% as determined by SDS-PAGE.

Recombinant Pig Leukocyte elastase inhibitor (SERPINB1)

Recombinant Pig Leukocyte elastase inhibitor (SERPINB1) — May be cleaved leading to a loss of its anti-protease activity and to the appearance of an endonuclease activity. Purity >85%.

SKU: BCRECP-004402 Category:
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Product Specifications

Product SkuBCRECP-004402
Product DescriptionRecombinant Pig Leukocyte elastase inhibitor (SERPINB1) Protein is expressed from E.coli with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 1-378aa. [Accession | P80229].
Uniprot No.P80229
Gene NamesSERPINB1
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-378aa
SpeciesSus scrofa (Pig)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight50.0kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCardiovascular

Function

May be cleaved leading to a loss of its anti-protease activity and to the appearance of an endonuclease activity. However no catalytic site was identified.

Biological Context

Subcellular Location: Secreted; Cytoplasm; Cytolytic granule; Early endosome

Product Specifications

Recombinant Pig Leukocyte elastase inhibitor (SERPINB1) is a recombinant protein from Sus scrofa (Pig), expressed in E.coli, covering amino acids 1-378aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 50.0kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

May be cleaved leading to a loss of its anti-protease activity and to the appearance of an endonuclease activity. However no catalytic site was identified

Subcellular Location

Secreted; Cytoplasm; Cytolytic granule; Early endosome

Subunit

Monomer. Interacts (via C-terminus) with CASP1; CASP4 (via CARD domain) and CASP5; these interactions regulate the activity of inflammatory caspases. Interacts with PRTN3. Interacts with GZMH

Gene: SERPINB1  |  Organism: Sus scrofa  |  Synonyms: Leukocyte neutral proteinase inhibitor; Serpin B1

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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