Recombinant Pig Vasopressin V2 receptor (AVPR2), partial, Sus scrofa (Pig), E.coli, N-terminal 6xHis-SUMO-tagged, 24.7kDa, purity >90% as determined by SDS-PAGE.

Recombinant Pig Vasopressin V2 receptor (AVPR2), partial

Recombinant Pig Vasopressin V2 receptor (AVPR2), partial — G protein-coupled receptor for arginine vasopressin, an antidiuretic that promotes renal water reabsorption. Purity >90%.

SKU: BCRECP-002168 Category:
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Product Specifications

Product SkuBCRECP-002168
Product DescriptionRecombinant Pig Vasopressin V2 receptor (AVPR2) Protein is expressed from E.coli with N-terminal 6xHis-SUMO-tagged. It contains 292-370aa. [Accession | P32307].
Uniprot No.P32307
Gene NamesAVPR2
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region292-370aa
SpeciesSus scrofa (Pig)
Tag InfoN-terminal 6xHis-SUMO-tagged
Molecular weight24.7kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

G protein-coupled receptor for arginine vasopressin, an antidiuretic that promotes renal water reabsorption. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase (cAMP). AVPR2 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity.

Biological Context

Subcellular Location: Cell membrane (Multi-pass membrane protein)

Product Specifications

Recombinant Pig Vasopressin V2 receptor (AVPR2), partial is a recombinant protein from Sus scrofa (Pig), expressed in E.coli, covering amino acids 292-370aa, with N-terminal 6xHis-SUMO-tagged tag, molecular weight 24.7kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

G protein-coupled receptor for arginine vasopressin, an antidiuretic that promotes renal water reabsorption (PubMed:8393786). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase (cAMP) (By similarity). AVPR2 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity (By similarity)

Subcellular Location

Cell membrane (Multi-pass membrane protein)

Subunit

Interacts with ARRDC4. Identified in a complex containing at least ARRDC4, V2R and HGS. Interacts with TMEM147. Interacts (when phosphorylated) with ARRB2; the interaction is associated with internalization of the receptor and short-term desensitization to the ligand

Gene: AVPR2  |  Organism: Sus scrofa  |  Synonyms: AVPR V2; Antidiuretic hormone receptor; Renal-type arginine vasopressin receptor

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Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

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Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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