Function
Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex, glycoprotein Ibalpha/IX/V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
Biological Context
Subcellular Location: Secreted; Secreted, extracellular space, extracellular matrix
Tissue Specificity: Plasma
Product Specifications
Recombinant Pig von Willebrand factor (VWF), partial is a recombinant protein from Sus scrofa (Pig), expressed in E.coli, covering amino acids 1167-1334aa, with C-terminal 6xHis-tagged tag, molecular weight 25.8kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.
