Recombinant Pongo abelii 2,3-cyclic-nucleotide 3-phosphodiesterase (CNP), Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), E.coli, N-terminal 10xHis-tagged and C-terminal Myc-tagged, 54.7kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Pongo abelii 2,3-cyclic-nucleotide 3-phosphodiesterase (CNP)

Recombinant Pongo abelii 2,3-cyclic-nucleotide 3-phosphodiesterase (CNP) — Myelin-associated enzyme that catalyzes the phosphodiester hydrolysis of 2′,3′-cyclic nucleotides to 2′-nucleotides. Purity >90%.

SKU: BCRECP-002403 Categories: ,
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Product Specifications

Product SkuBCRECP-002403
Product DescriptionRecombinant Pongo abelii 2,3-cyclic-nucleotide 3-phosphodiesterase (CNP) Protein is expressed from E.coli with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 1-418aa. [Accession | Q5RFD0].
Uniprot No.Q5RFD0
Gene NamesCNP
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-418aa
SpeciesPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight54.7kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasNeuroscience

Function

Myelin-associated enzyme that catalyzes the phosphodiester hydrolysis of 2',3'-cyclic nucleotides to 2'-nucleotides. In the mitochondria, regulates the functioning of the mitochondrial permeability transition pore (mPTP), and thus is involved in the mechanisms of cell death, both apoptosis and necrosis. Acts as an antiviral factor by suppressing the assembly of SARS-CoV-2 virions.

Biological Context

Subcellular Location: Melanosome; Mitochondrion

Product Specifications

Recombinant Pongo abelii 2,3-cyclic-nucleotide 3-phosphodiesterase (CNP) is a recombinant protein from Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii), expressed in E.coli, covering amino acids 1-418aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 54.7kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Myelin-associated enzyme that catalyzes the phosphodiester hydrolysis of 2',3'-cyclic nucleotides to 2'-nucleotides. In the mitochondria, regulates the functioning of the mitochondrial permeability transition pore (mPTP), and thus is involved in the mechanisms of cell death, both apoptosis and necrosis. Acts as an antiviral factor by suppressing the assembly of SARS-CoV-2 virions

Subcellular Location

Melanosome; Mitochondrion

Subunit

Exists as monomers and homodimers

Gene: CNP  |  Organism: Pongo abelii

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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