Recombinant Pongo pygmaeus Beta-defensin 126 (DEFB126), partial

Recombinant Pongo pygmaeus Beta-defensin 126 (DEFB126), partial — Highly glycosylated atypical beta-defensin involved in several aspects of sperm function. Purity >90%.

SKU: BCRECP-002526 Category:

Product Specifications

Product SkuBCRECP-002526
Product DescriptionRecombinant Pongo pygmaeus Beta-defensin 126 (DEFB126) Protein is expressed from Yeast with N-terminal GST-tagged. It contains 21-63aa. [Accession | A4H244].
Uniprot No.A4H244
Gene NamesDEFB126
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemYeast
Expression Region21-63aa
SpeciesPongo pygmaeus (Bornean orangutan)
Tag InfoN-terminal GST-tagged
Molecular weight31.9kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Highly glycosylated atypical beta-defensin involved in several aspects of sperm function. Facilitates sperm transport in the female reproductive tract and contributes to sperm protection against immunodetection; both functions are probably implicating the negative surface charge provided by its O-linked oligosaccharides in the sperm glycocalyx.

Product Specifications

Recombinant Pongo pygmaeus Beta-defensin 126 (DEFB126), partial — Highly glycosylated atypical beta-defensin involved in several aspects of sperm function. Purity >90%. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Highly glycosylated atypical beta-defensin involved in several aspects of sperm function. Facilitates sperm transport in the female reproductive tract and contributes to sperm protection against immunodetection; both functions are probably implicating the negative surface charge provided by its O-linked oligosaccharides in the sperm glycocalyx. Involved in binding of sperm to oviductal epithelial cells to form a sperm reservoir until ovulation. Release from the sperm surface during capacitation and ovaluation by an elevation of oviductal fluid pH is unmasking other surface components and allows sperm to penetrate the cumulus matrix and bind to the zona pellucida of the oocyte. In vitro has antimicrobial activity and may inhibit LPS-mediated inflammation (By similarity)

Subcellular Location

Secreted

Subunit

Homodimer or homooligomer; disulfide-linked

Gene: DEFB126  |  Organism: Pongo pygmaeus  |  Synonyms: Defensin, beta 126

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

Shopping Cart
Scroll to Top