Recombinant Rabbit Fibroblast growth factor 2 (FGF2), partial, Oryctolagus cuniculus (Rabbit), E.coli, N-terminal 6xHis-SUMO-tagged, 28.4kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Rabbit Fibroblast growth factor 2 (FGF2), partial

Recombinant Rabbit Fibroblast growth factor 2 (FGF2), partial — Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Purity >90%.

SKU: BCRECP-002727 Categories: ,
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Product Specifications

Product SkuBCRECP-002727
Product DescriptionRecombinant Rabbit Fibroblast growth factor 2 (FGF2) Protein is expressed from E.coli with N-terminal 6xHis-SUMO-tagged. It contains 1-137aa. [Accession | P48799].
Uniprot No.P48799
Gene NamesFGF2
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-137aa
SpeciesOryctolagus cuniculus (Rabbit)
Tag InfoN-terminal 6xHis-SUMO-tagged
Molecular weight28.4kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3.

Biological Context

Subcellular Location: Secreted; Nucleus

Product Specifications

Recombinant Rabbit Fibroblast growth factor 2 (FGF2), partial is a recombinant protein from Oryctolagus cuniculus (Rabbit), expressed in E.coli, covering amino acids 1-137aa, with N-terminal 6xHis-SUMO-tagged tag, molecular weight 28.4kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity). Also acts as an integrin ligand which is required for FGF2 signaling (By similarity). Binds to integrin ITGAV:ITGB3 (By similarity). Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration (By similarity). Functions as a potent mitogen in vitro (By similarity). Can induce angiogenesis (By similarity). Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation (By similarity)

Subcellular Location

Secreted; Nucleus

Subunit

Monomer. Homodimer. Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors. Interacts with CSPG4, FGFBP1 and TEC. Found in a complex with FGFBP1, FGF1 and FGF2. Interacts with FGFBP3. Interacts with integrin ITGAV:ITGB3; the interaction is required for FGF2 signaling. Interacts with SNORC (via the extracellular domain). Interacts with glypican GPC3

Gene: FGF2  |  Organism: Oryctolagus cuniculus  |  Synonyms: Basic fibroblast growth factor; Heparin-binding growth factor 2

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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