Recombinant Rat Aggrecan core protein (Acan), partial, Rattus norvegicus (Rat), E.coli, C-terminal 6xHis-tagged, 19.5kDa, purity >85% as determined by SDS-PAGE.

Recombinant Rat Aggrecan core protein (Acan), partial

Recombinant Rat Aggrecan core protein (Acan), partial — This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. Purity >85%.

SKU: BCRECP-001995 Category:
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Product Specifications

Product SkuBCRECP-001995
Product DescriptionRecombinant Rat Aggrecan core protein (Acan) Protein is expressed from E.coli with C-terminal 6xHis-tagged. It contains 34-147aa. [Accession | P07897].
Uniprot No.P07897
Gene NamesAcan
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region34-147aa
SpeciesRattus norvegicus (Rat)
Tag InfoC-terminal 6xHis-tagged
Molecular weight19.5kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasSignal Transduction

Function

This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region.

Biological Context

Subcellular Location: Secreted, extracellular space, extracellular matrix

Product Specifications

Recombinant Rat Aggrecan core protein (Acan), partial is a recombinant protein from Rattus norvegicus (Rat), expressed in E.coli, covering amino acids 34-147aa, with C-terminal 6xHis-tagged tag, molecular weight 19.5kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage

Subcellular Location

Secreted, extracellular space, extracellular matrix

Subunit

Forms a complex (via covalent bonds) with MATN1; the interaction increases with age of the organism via an increase in occupancy of MATN1 binding sites (By similarity). Interacts with FBLN1 (By similarity). Interacts with COMP (By similarity)

Gene: Acan  |  Organism: Rattus norvegicus  |  Synonyms: Cartilage-specific proteoglycan core protein

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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