Recombinant Rat Alpha-1-antiproteinase (Serpina1)

Recombinant Rat Alpha-1-antiproteinase (Serpina1) — Inhibitor of serine proteases. Purity >90%.

SKU: BCRECP-004394 Category:

Product Specifications

Product SkuBCRECP-004394
Product DescriptionRecombinant Rat Alpha-1-antiproteinase (Serpina1) Protein is expressed from E.coli with N-terminal 6xHis-SUMO-tagged. It contains 25-411aa. [Accession | P17475].
Uniprot No.P17475
Gene NamesSerpina1
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region25-411aa
SpeciesRattus norvegicus (Rat)
Tag InfoN-terminal 6xHis-SUMO-tagged
Molecular weight59.7kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasImmunology

Function

Inhibitor of serine proteases. The primary target is elastase, but also has a moderate affinity for plasmin and thrombin.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Plasma

Product Specifications

Recombinant Rat Alpha-1-antiproteinase (Serpina1) is a recombinant protein from Rattus norvegicus (Rat), expressed in E.coli, covering amino acids 25-411aa, with N-terminal 6xHis-SUMO-tagged tag, molecular weight 59.7kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Inhibitor of serine proteases. The primary target is elastase, but also has a moderate affinity for plasmin and thrombin

Subcellular Location

Secreted

Tissue Specificity

Plasma

Subunit

Interacts with CELA2A (By similarity). Interacts with ERGIC3 and LMAN1/ERGIC53 (By similarity). Interacts with PRSS1/Trypsin (By similarity)

Gene: Serpina1  |  Organism: Rattus norvegicus  |  Synonyms: Alpha-1-antitrypsin; Alpha-1-proteinase inhibitor; Serpin A1

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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