Recombinant Rat Chitinase-3-like protein 1 (Chi3l1), Rattus norvegicus (Rat), E.coli, N-terminal 10xHis-tagged and C-terminal Myc-tagged, 45.4kDa, purity >90% as determined by SDS-PAGE.

Recombinant Rat Chitinase-3-like protein 1 (Chi3l1)

Recombinant Rat Chitinase-3-like protein 1 (Chi3l1) — Carbohydrate-binding lectin with a preference for chitin. Purity >90%.

SKU: BCRECP-002365 Category:
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Product Specifications

Product SkuBCRECP-002365
Product DescriptionRecombinant Rat Chitinase-3-like protein 1 (Chi3l1) Protein is expressed from E.coli with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 20-381aa. [Accession | Q9WTV1].
Uniprot No.Q9WTV1
Gene NamesChi3l1
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region20-381aa
SpeciesRattus norvegicus (Rat)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight45.4kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment.

Biological Context

Subcellular Location: Secreted, extracellular space; Cytoplasm; Cytoplasm, perinuclear region; Endoplasmic reticulum

Product Specifications

Recombinant Rat Chitinase-3-like protein 1 (Chi3l1) is a recombinant protein from Rattus norvegicus (Rat), expressed in E.coli, covering amino acids 20-381aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 45.4kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung (By similarity)

Subcellular Location

Secreted, extracellular space; Cytoplasm; Cytoplasm, perinuclear region; Endoplasmic reticulum

Subunit

Monomer

Gene: Chi3l1  |  Organism: Rattus norvegicus  |  Synonyms: Cartilage glycoprotein 39

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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