Recombinant Rat Glucagon-like peptide 1 receptor (Glp1r), partial

Recombinant Rat Glucagon-like peptide 1 receptor (Glp1r), partial — G protein-coupled receptor for glucagon-like peptide 1 (GLP-1). Purity >95%.

SKU: BCRECP-002874 Category:

Product Specifications

Product SkuBCRECP-002874
Product DescriptionRecombinant Rat Glucagon-like peptide 1 receptor (Glp1r) Protein is expressed from Yeast with N-terminal 6xHis-tagged. It contains 22-139aa. [Accession | P32301].
Uniprot No.P32301
Gene NamesGlp1r
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemYeast
Expression Region22-139aa
SpeciesRattus norvegicus (Rat)
Tag InfoN-terminal 6xHis-tagged
Molecular weight15.6kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasNeuroscience

Function

G protein-coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1.

Biological Context

Subcellular Location: Cell membrane (Multi-pass membrane protein)
Tissue Specificity: Pancreatic islets, stomach, lung, rat insulinoma cell line

Product Specifications

Recombinant Rat Glucagon-like peptide 1 receptor (Glp1r), partial is a recombinant protein from Rattus norvegicus (Rat), expressed in Yeast, covering amino acids 22-139aa, with N-terminal 6xHis-tagged tag, molecular weight 15.6kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

G protein-coupled receptor for glucagon-like peptide 1 (GLP-1) (PubMed:1326760, PubMed:7527026, PubMed:7813606). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels (PubMed:1326760, PubMed:7813606). Plays a role in regulating insulin secretion in response to GLP-1 (By similarity)

Subcellular Location

Cell membrane (Multi-pass membrane protein)

Tissue Specificity

Pancreatic islets, stomach, lung, rat insulinoma cell line

Subunit

May form homodimers and heterodimers with GIPR

Gene: Glp1r  |  Organism: Rattus norvegicus

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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