Recombinant Rat Haptoglobin (Hp), partial, Rattus norvegicus (Rat), E.coli, N-terminal 6xHis-tagged, 40.5kDa, purity >90% as determined by SDS-PAGE.

Recombinant Rat Haptoglobin (Hp), partial

Recombinant Rat Haptoglobin (Hp), partial — As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Purity >90%.

SKU: BCRECP-003013 Category:
Online Inquiry →

Product Specifications

Product SkuBCRECP-003013
Product DescriptionRecombinant Rat Haptoglobin (Hp) Protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 19-346aa. [Accession | P06866].
Uniprot No.P06866
Gene NamesHP
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region19-346aa
SpeciesRattus norvegicus (Rat)
Tag InfoN-terminal 6xHis-tagged
Molecular weight40.5kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasEpigenetics and Nuclear Signaling

Function

As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Expressed by the liver and secreted in plasma

Product Specifications

Recombinant Rat Haptoglobin (Hp), partial is a recombinant protein from Rattus norvegicus (Rat), expressed in E.coli, covering amino acids 19-346aa, with N-terminal 6xHis-tagged tag, molecular weight 40.5kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway (By similarity)

Subcellular Location

Secreted

Tissue Specificity

Expressed by the liver and secreted in plasma

Subunit

Tetramer of two alpha and two beta chains; disulfide-linked (By similarity). The hemoglobin/haptoglobin complex is composed of a haptoglobin dimer bound to two hemoglobin alpha-beta dimers (By similarity). Interacts with CD163 (By similarity). Interacts with ERGIC3 (By similarity)

Gene: Hp  |  Organism: Rattus norvegicus  |  Synonyms: Liver regeneration-related protein LRRG173
Key Publications

Explore closely related product collections, technology platforms, and custom production resources.

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

Shopping Cart
Scroll to Top