Recombinant Rat Klotho (Kl), partial, Rattus norvegicus (Rat), E.coli, N-terminal 6xHis-tagged, 64.9kDa, purity >85% as determined by SDS-PAGE.

Recombinant Rat Klotho (Kl), partial

Recombinant Rat Klotho (Kl), partial — recombinant protein from Rattus norvegicus (Rat), expressed in E.coli. Purity >85%.

SKU: BCRECP-003215 Category:
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Product Specifications

Product SkuBCRECP-003215
Product DescriptionRecombinant Rat Klotho (Kl) Protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 35-550aa. [Accession | Q9Z2Y9].
Uniprot No.Q9Z2Y9
Gene NamesKl
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region35-550aa
SpeciesRattus norvegicus (Rat)
Tag InfoN-terminal 6xHis-tagged
Molecular weight64.9kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

The Klotho peptide generated by cleavage of the membrane-bound isoform may be an anti-aging circulating hormone which would extend life span by inhibiting insulin/IGF1 signaling.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Present in cortical renal tubules and the parathyroid (at protein level). Strongly expressed in kidney. Expressed at low levels in brain, lung, intestine and ovaries

Product Specifications

Recombinant Rat Klotho (Kl), partial is a recombinant protein from Rattus norvegicus (Rat), expressed in E.coli, covering amino acids 35-550aa, with N-terminal 6xHis-tagged tag, molecular weight 64.9kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Related products

Protein Biology

Function

The Klotho peptide generated by cleavage of the membrane-bound isoform may be an anti-aging circulating hormone which would extend life span by inhibiting insulin/IGF1 signaling

Subcellular Location

Secreted

Tissue Specificity

Present in cortical renal tubules and the parathyroid (at protein level). Strongly expressed in kidney. Expressed at low levels in brain, lung, intestine and ovaries

Subunit

Homodimer. Interacts with FGF23 and FGFR1

Gene: Kl  |  Organism: Rattus norvegicus
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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