Recombinant Rat Protein S100-A6 (S100a6), Rattus norvegicus (Rat), E.coli, N-terminal 10xHis-tagged, 13.7kDa, purity >90% as determined by SDS-PAGE.

Recombinant Rat Protein S100-A6 (S100a6)

Recombinant Rat Protein S100-A6 (S100a6) — May function as calcium sensor and modulator, contributing to cellular calcium signaling. Purity >90%.

SKU: BCRECP-004349 Category:
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Product Specifications

Product SkuBCRECP-004349
Product DescriptionRecombinant Rat Protein S100-A6 (S100a6) Protein is expressed from E.coli with N-terminal 10xHis-tagged. It contains 1-89aa. [Accession | P05964].
Uniprot No.P05964
Gene NamesS100a6
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-89aa
SpeciesRattus norvegicus (Rat)
Tag InfoN-terminal 10xHis-tagged
Molecular weight13.7kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions.

Biological Context

Subcellular Location: Nucleus envelope; Cytoplasm; Cell membrane (Peripheral membrane protein)

Product Specifications

Recombinant Rat Protein S100-A6 (S100a6) is a recombinant protein from Rattus norvegicus (Rat), expressed in E.coli, covering amino acids 1-89aa, with N-terminal 10xHis-tagged tag, molecular weight 13.7kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative (By similarity)

Subcellular Location

Nucleus envelope; Cytoplasm; Cell membrane (Peripheral membrane protein)

Subunit

Homodimer; head to tail assembly of 2 subunits. Interacts with CACYBP in a calcium-dependent manner. Interacts with ANXA2 and ANXA11 (via N-terminus). Interacts with SUGT1. Interacts with TP53; has higher affinity for TP53 that is phosphorylated on its N-terminal domain, and lower affinity for TP53 that is phosphorylated on its C-terminal domain. Interacts with tropomyosin. Interacts with FKBP4. Interacts with PPP5C (via TPR repeats); the interaction is calcium-dependent and modulates PPP5C activity. Interacts with TPPP; this interaction inhibits TPPP dimerization (By similarity)

Gene: S100a6  |  Organism: Rattus norvegicus  |  Synonyms: Calcyclin; Prolactin receptor-associated protein; S100 calcium-binding protein A6

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Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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