Recombinant Rat Secretogranin-3 (Scg3), Rattus norvegicus (Rat), E.coli, N-terminal 10xHis-tagged and C-terminal Myc-tagged, 58.2kDa, purity >90% as determined by SDS-PAGE.

Recombinant Rat Secretogranin-3 (Scg3)

Recombinant Rat Secretogranin-3 (Scg3) — Member of the granin protein family that regulates the biogenesis of secretory granules. Purity >90%.

SKU: BCRECP-004378 Category:
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Product Specifications

Product SkuBCRECP-004378
Product DescriptionRecombinant Rat Secretogranin-3 (Scg3) Protein is expressed from E.coli with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 23-471aa. [Accession | P47868].
Uniprot No.P47868
Gene NamesScg3
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region23-471aa
SpeciesRattus norvegicus (Rat)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight58.2kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasNeuroscience

Function

Member of the granin protein family that regulates the biogenesis of secretory granules. Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA. May also play a role in angiogenesis.

Biological Context

Subcellular Location: Cytoplasmic vesicle, secretory vesicle; Cytoplasmic vesicle, secretory vesicle membrane (Peripheral membrane protein); Secreted
Tissue Specificity: Expression restricted to the brain and pituitary gland. Not detected in the adrenal gland

Product Specifications

Recombinant Rat Secretogranin-3 (Scg3) is a recombinant protein from Rattus norvegicus (Rat), expressed in E.coli, covering amino acids 23-471aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 58.2kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Member of the granin protein family that regulates the biogenesis of secretory granules (PubMed:12388744, PubMed:14597614). Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA (PubMed:12388744, PubMed:14597614). May also play a role in angiogenesis. Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway (By similarity)

Subcellular Location

Cytoplasmic vesicle, secretory vesicle; Cytoplasmic vesicle, secretory vesicle membrane (Peripheral membrane protein); Secreted

Tissue Specificity

Expression restricted to the brain and pituitary gland. Not detected in the adrenal gland

Subunit

Interacts with CHGA (PubMed:12388744). Interacts with secretogranin II/SCG2 (By similarity). Interacts (via C-terminus) with CPE (By similarity)

Gene: Scg3  |  Organism: Rattus norvegicus  |  Synonyms: 1B1075; Secretogranin III
Key Publications

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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