Recombinant Rat Urokinase plasminogen activator surface receptor (Plaur), Rattus norvegicus (Rat), E.coli, N-terminal 6xHis-tagged, 34.1kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Rat Urokinase plasminogen activator surface receptor (Plaur)

Recombinant Rat Urokinase plasminogen activator surface receptor (Plaur) — GPI-anchored receptor that recruits and activates the urokinase-type plasminogen activator (uPA) at the cell surface. Purity >90%.

SKU: BCRECP-004095 Categories: ,
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Product Specifications

Product SkuBCRECP-004095
Product DescriptionRecombinant Rat Urokinase plasminogen activator surface receptor (Plaur) Protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 25-299aa. [Accession | P49616].
Uniprot No.P49616
Gene NamesPlaur
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region25-299aa
SpeciesRattus norvegicus (Rat)
Tag InfoN-terminal 6xHis-tagged
Molecular weight34.1kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

GPI-anchored receptor that recruits and activates the urokinase-type plasminogen activator (uPA) at the cell surface. Activated uPA converts plasminogen into plasmin, initiating extracellular matrix degradation and remodeling. Also binds the extracellular matrix protein vitronectin, promoting cell-matrix adhesion and indirectly integrin signaling.

Biological Context

Subcellular Location: Secreted

Product Specifications

Recombinant Rat Urokinase plasminogen activator surface receptor (Plaur) is a recombinant protein from Rattus norvegicus (Rat), expressed in E.coli, covering amino acids 25-299aa, with N-terminal 6xHis-tagged tag, molecular weight 34.1kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

GPI-anchored receptor that recruits and activates the urokinase-type plasminogen activator (uPA) at the cell surface. Activated uPA converts plasminogen into plasmin, initiating extracellular matrix degradation and remodeling. Also binds the extracellular matrix protein vitronectin, promoting cell-matrix adhesion and indirectly integrin signaling. This dual interaction coordinates dynamic changes in cell migration, proliferation, and tissue remodeling

Subcellular Location

Secreted

Subunit

Monomer (Probable). Interacts (via the UPAR/Ly6 domains) with SRPX2. Interacts with MRC2 (By similarity). Interacts with SORL1 (via N-terminal ectodomain); this interaction decreases PLAUR internalization (By similarity). The ternary complex composed of PLAUR-PLAU-SERPINE1 also interacts with SORL1 (By similarity). Interacts with CD82; this interaction prevents PLAUR from binding to its high affinity ligand PLAU (By similarity)

Gene: Plaur  |  Organism: Rattus norvegicus

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Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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