Recombinant Serratia marcescens Metallo-beta-lactamase type 2, partial

Recombinant Serratia marcescens Metallo-beta-lactamase type 2, partial — Class B beta-lactamase which confers resistance to the beta-lactam antibiotics, including penicillins, cephalosporins and carbapenems. Purity >90%.

SKU: BCRECP-003642 Category:

Product Specifications

Product SkuBCRECP-003642
Product DescriptionRecombinant Serratia marcescens Metallo-beta-lactamase type 2, partial Protein is expressed from E.coli with N-terminal 10XHis-SUMO-tagged and C-terminal Myc-tagged. It contains 20-246aa. [Accession | P52699].
Uniprot No.P52699
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region20-246aa
SpeciesSerratia marcescens
Tag InfoN-terminal 10XHis-SUMO-tagged and C-terminal Myc-tagged
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Class B beta-lactamase which confers resistance to the beta-lactam antibiotics, including penicillins, cephalosporins and carbapenems. Acts via hydrolysis of the beta-lactam ring. Has penicillin-, cephalosporin- and carbapenem-hydrolyzing activities.

Product Specifications

Recombinant Serratia marcescens Metallo-beta-lactamase type 2, partial is a recombinant protein, expressed in E.coli, covering amino acids 20-246aa, with N-terminal 10XHis-SUMO-tagged and C-terminal Myc-tagged tag, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Class B beta-lactamase which confers resistance to the beta-lactam antibiotics, including penicillins, cephalosporins and carbapenems (PubMed:10898670, PubMed:29485857, PubMed:8141584). Acts via hydrolysis of the beta-lactam ring (PubMed:10898670, PubMed:15788415). Has penicillin-, cephalosporin- and carbapenem-hydrolyzing activities (PubMed:10898670, PubMed:15788415, PubMed:15892033). Has endoribonuclease activity, cleaving substrate RNAs preferentially between U/C and A, in vitro (PubMed:33126240)

Organism: Serratia marcescens

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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