Recombinant Staphylococcus aureus Chemotaxis inhibitory protein (chp), Staphylococcus aureus (strain NCTC 8325 / PS 47), E.coli, N-terminal 10xHis-tagged and C-terminal Myc-tagged, 21.5kDa, purity >90% as determined by SDS-PAGE.

Recombinant Staphylococcus aureus Chemotaxis inhibitory protein (chp)

Recombinant Staphylococcus aureus Chemotaxis inhibitory protein (chp) — Involved in countering the first line of host defense mechanisms. Purity >90%.

SKU: BCRECP-002367 Category:
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Product Specifications

Product SkuBCRECP-002367
Product DescriptionRecombinant Staphylococcus aureus Chemotaxis inhibitory protein (chp) Protein is expressed from E.coli with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 29-149aa. [Accession | Q2FWV5].
Uniprot No.Q2FWV5
Gene Nameschp
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region29-149aa
SpeciesStaphylococcus aureus (strain NCTC 8325 / PS 47)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight21.5kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leucyl-phenylalanine (fMLP). Acts by binding directly to the C5a receptor (C5aR) and formylated peptide receptor (FPR), thereby blocking the C5a- and fMLP-induced calcium responses.

Biological Context

Subcellular Location: Secreted

Product Specifications

Recombinant Staphylococcus aureus Chemotaxis inhibitory protein (chp) is a recombinant protein from Staphylococcus aureus (strain NCTC 8325 / PS 47), expressed in E.coli, covering amino acids 29-149aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 21.5kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leucyl-phenylalanine (fMLP). Acts by binding directly to the C5a receptor (C5aR) and formylated peptide receptor (FPR), thereby blocking the C5a- and fMLP-induced calcium responses (By similarity). Prevents phagocytosis of the bacterium

Subcellular Location

Secreted

Gene: chp  |  Organism: Staphylococcus aureus (strain NCTC 8325 / PS 47)  |  Synonyms: CHIPS

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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