Recombinant Staphylococcus aureus Chemotaxis inhibitory protein (chp), Staphylococcus aureus (strain NCTC 8325 / PS 47), E.coli, N-terminal 10xHis-tagged and C-terminal Myc-tagged, 21.5kDa, purity >90% as determined by SDS-PAGE.

Recombinant Staphylococcus aureus Chemotaxis inhibitory protein (chp)

Recombinant Staphylococcus aureus Chemotaxis inhibitory protein (chp) — Involved in countering the first line of host defense mechanisms. Purity >90%.

SKU: BCRECP-002367 Category:
Online Inquiry →

Product Specifications

Product SkuBCRECP-002367
Product DescriptionRecombinant Staphylococcus aureus Chemotaxis inhibitory protein (chp) Protein is expressed from E.coli with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 29-149aa. [Accession | Q2FWV5].
Uniprot No.Q2FWV5
Gene Nameschp
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region29-149aa
SpeciesStaphylococcus aureus (strain NCTC 8325 / PS 47)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight21.5kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leucyl-phenylalanine (fMLP). Acts by binding directly to the C5a receptor (C5aR) and formylated peptide receptor (FPR), thereby blocking the C5a- and fMLP-induced calcium responses.

Biological Context

Subcellular Location: Secreted

Product Specifications

Recombinant Staphylococcus aureus Chemotaxis inhibitory protein (chp) is a recombinant protein from Staphylococcus aureus (strain NCTC 8325 / PS 47), expressed in E.coli, covering amino acids 29-149aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 21.5kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

Involved in countering the first line of host defense mechanisms. Specifically inhibits the response of human neutrophils and monocytes to complement anaphylatoxin C5a and formylated peptides, like N-formyl-methionyl-leucyl-phenylalanine (fMLP). Acts by binding directly to the C5a receptor (C5aR) and formylated peptide receptor (FPR), thereby blocking the C5a- and fMLP-induced calcium responses (By similarity). Prevents phagocytosis of the bacterium

Subcellular Location

Secreted

Gene: chp  |  Organism: Staphylococcus aureus (strain NCTC 8325 / PS 47)  |  Synonyms: CHIPS

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

Shopping Cart
Scroll to Top