Recombinant Staphylococcus aureus Enterotoxin type A (entA), partial

Recombinant Staphylococcus aureus Enterotoxin type A (entA), partial — Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. Purity >85%.

SKU: BCRECP-002614 Category:

Product Specifications

Product SkuBCRECP-002614
Product DescriptionRecombinant Staphylococcus aureus Enterotoxin type A (entA) Protein is expressed from E.coli with N-terminal 6xHis-tagged. It contains 25-253aa. [Accession | P0A0L2].
Uniprot No.P0A0L2
Gene NamesentA
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region25-253aa
SpeciesStaphylococcus aureus
Tag InfoN-terminal 6xHis-tagged
Molecular weight30.5kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasCell Biology

Function

Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, waves of cellular activation, cytokine production, and migration into the lung tissue and airways occur via alphabeta T-cells.

Product Specifications

Recombinant Staphylococcus aureus Enterotoxin type A (entA), partial — Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. Purity >85%. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules (PubMed:12467569, PubMed:2658055). In turn, waves of cellular activation, cytokine production, and migration into the lung tissue and airways occur via alphabeta T-cells (PubMed:23321986). Also causes the intoxication staphylococcal food poisoning syndrome. The illness is characterized by high fever, hypotension, diarrhea, shock, and in some cases death (Probable)

Subcellular Location

Secreted

Subunit

Monomer. Interacts with MHC class II molecules alpha/HLA-DRB1 and beta/HLA-DRA chains (PubMed:11847286, PubMed:12467569, PubMed:2658055). The interaction with MHC-II molecules occurs at both zinc-dependent and zinc-independent sites (PubMed:12467569, PubMed:2658055). Interacts with T-cell receptor beta variable 7-9/TRBV7-9 (PubMed:27180909)

Gene: entA  |  Organism: Staphylococcus aureus  |  Synonyms: SEA
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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