Recombinant Streptococcus pyogenes DNA-binding protein HU (hup), Streptococcus pyogenes, E.coli, N-terminal 10xHis-tagged and C-terminal Myc-tagged, 17.1kDa, purity >90% as determined by SDS-PAGE.

Recombinant Streptococcus pyogenes DNA-binding protein HU (hup)

Recombinant Streptococcus pyogenes DNA-binding protein HU (hup) — Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Purity >90%.

SKU: BCRECP-003040 Category:
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Product Specifications

Product SkuBCRECP-003040
Product DescriptionRecombinant Streptococcus pyogenes DNA-binding protein HU (hup) Protein is expressed from E.coli with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 1-91aa. [Accession | P0C0H2].
Uniprot No.P0C0H2
Gene Nameshup
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region1-91aa
SpeciesStreptococcus pyogenes
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight17.1kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasNeuroscience

Function

Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Also seems to act as a fortuitous virulence factor in delayed sequelae by binding to heparan sulfate-proteoglycans in the extracellular matrix of target organs and acting as a nidus for in situ immune complex formation.

Product Specifications

Recombinant Streptococcus pyogenes DNA-binding protein HU (hup) is a recombinant protein from Streptococcus pyogenes, expressed in E.coli, covering amino acids 1-91aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 17.1kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Also seems to act as a fortuitous virulence factor in delayed sequelae by binding to heparan sulfate-proteoglycans in the extracellular matrix of target organs and acting as a nidus for in situ immune complex formation

Gene: hup  |  Organism: Streptococcus pyogenes

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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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