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Recombinant Varicella-zoster virus Envelope glycoprotein B (gB), partial

Recombinant Varicella-zoster virus Envelope glycoprotein B (gB), partial — Envelope glycoprotein that forms spikes at the surface of virion envelope. Purity >95%.

SKU: BCRECP-002828 Categories: ,

Product Specifications

Product SkuBCRECP-002828
Product DescriptionRecombinant Varicella-zoster virus Envelope glycoprotein B (gB) Protein is expressed from Yeast with C-terminal hFc1-tagged. It contains 176-274aa. [Accession | Q4JR05].
Uniprot No.Q4JR05
Gene NamesgB
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemYeast
Expression Region176-274aa
SpeciesVaricella-zoster virus (strain Oka vaccine) (HHV-3) (Human herpesvirus 3)
Tag InfoC-terminal hFc1-tagged
Molecular weight37.5kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Envelope glycoprotein that forms spikes at the surface of virion envelope. Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell.

Biological Context

Subcellular Location: Virion membrane (Single-pass type I membrane protein); Host cell membrane (Single-pass type I membrane protein); Host endosome membrane (Single-pass type I membrane protein); Host Golgi apparatus membrane (Single-pass type I membrane protein)

Product Specifications

Recombinant Varicella-zoster virus Envelope glycoprotein B (gB), partial is a recombinant protein from Varicella-zoster virus (strain Oka vaccine) (HHV-3) (Human herpesvirus 3), expressed in Yeast, covering amino acids 176-274aa, with C-terminal hFc1-tagged tag, molecular weight 37.5kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Please contact us to obtain bioactivity data.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Envelope glycoprotein that forms spikes at the surface of virion envelope. Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell. Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress

Subcellular Location

Virion membrane (Single-pass type I membrane protein); Host cell membrane (Single-pass type I membrane protein); Host endosome membrane (Single-pass type I membrane protein); Host Golgi apparatus membrane (Single-pass type I membrane protein)

Subunit

Homotrimer; disulfide-linked. Binds to heparan sulfate proteoglycans. Interacts with gH/gL heterodimer

Gene: gB  |  Organism: Varicella-zoster virus (strain Oka vaccine)

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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