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Recombinant Varicella-zoster virus Tegument protein UL47 homolog (ORF11), partial

Recombinant Varicella-zoster virus Tegument protein UL47 homolog (ORF11), partial — Tegument protein that can bind to various RNA transcripts. Purity >85%.

SKU: BCRECP-003967 Categories: ,

Product Specifications

Product SkuBCRECP-003967
Product DescriptionRecombinant Varicella-zoster virus Tegument protein UL47 homolog (ORF11) Protein is expressed from E.coli with N-terminal 10xHis-tagged and C-terminal Myc-tagged. It contains 354-808aa. [Accession | P09263].
Uniprot No.P09263
Gene NamesORF11
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemE.coli
Expression Region354-808aa
SpeciesVaricella-zoster virus (strain Dumas) (HHV-3) (Human herpesvirus 3)
Tag InfoN-terminal 10xHis-tagged and C-terminal Myc-tagged
Molecular weight58.3kDa
ActivityPlease contact us to obtain bioactivity data.
BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Research AreasOthers

Function

Tegument protein that can bind to various RNA transcripts. Plays a role in the attenuation of selective viral and cellular mRNA degradation by modulating the activity of host shutoff RNase ORF17/VHS. Also plays a role in the primary envelopment of virions in the perinuclear space, probably by interacting with two nuclear egress proteins ORF24 and ORF27.

Biological Context

Subcellular Location: Virion tegument; Host nucleus; Host cytoplasm

Product Specifications

Recombinant Varicella-zoster virus Tegument protein UL47 homolog (ORF11), partial is a recombinant protein from Varicella-zoster virus (strain Dumas) (HHV-3) (Human herpesvirus 3), expressed in E.coli, covering amino acids 354-808aa, with N-terminal 10xHis-tagged and C-terminal Myc-tagged tag, molecular weight 58.3kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Protein Biology

Function

Tegument protein that can bind to various RNA transcripts. Plays a role in the attenuation of selective viral and cellular mRNA degradation by modulating the activity of host shutoff RNase ORF17/VHS. Also plays a role in the primary envelopment of virions in the perinuclear space, probably by interacting with two nuclear egress proteins ORF24 and ORF27

Subcellular Location

Virion tegument; Host nucleus; Host cytoplasm

Subunit

Interacts with US3 kinase. Interacts with ORF24 and ORF27; these interactions seem important for efficient virion nuclear egress. Interacts with ORF17/VHS. Interacts with ORF9

Organism: Varicella-zoster virus (strain Dumas)

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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