Mouse anti-Human sapiens (Human) MAGEA4 Monoclonal Antibody
Mouse anti-Human sapiens (Human) MAGEA4 Monoclonal Antibody - Image 2
Mouse anti-Human sapiens (Human) MAGEA4 Monoclonal Antibody - Image 3
Mouse anti-Human sapiens (Human) MAGEA4 Monoclonal Antibody - Image 4
Mouse anti-Human sapiens (Human) MAGEA4 Monoclonal Antibody - Image 5

Mouse anti-Human sapiens (Human) MAGEA4 Monoclonal Antibody

Mouse anti-Human sapiens (Human) MAGEA4 Monoclonal Antibody — Regulates cell proliferation through the inhibition of cell cycle arrest at the G1 phase.

SKU: BCREC-000181MA Category:
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Product Specifications

Uniprot No.P43358
Target NamesMAGEA4
Species ReactivityMouse
ImmunogenRecombinant Human Melanoma-associated antigen 4 protein (1-317AA)
ConjugateNon-conjugated
IsotypeIgG1
ClonalityMonoclonal
ApplicationsELISA, IHC, FC
BufferPBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Function

Regulates cell proliferation through the inhibition of cell cycle arrest at the G1 phase. Also negatively regulates p53-mediated apoptosis.

Biological Context

Tissue Specificity: Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta

Product Specifications

Mouse anti-Human sapiens (Human) MAGEA4 Monoclonal Antibody is a recombinant protein. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Regulates cell proliferation through the inhibition of cell cycle arrest at the G1 phase (PubMed:22842486). Also negatively regulates p53-mediated apoptosis (PubMed:22842486)

Tissue Specificity

Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta

Gene: MAGEA4  |  Organism: Homo sapiens  |  Synonyms: Cancer/testis antigen 1.4; MAGE-4 antigen; MAGE-41 antigen; MAGE-X2 antigen
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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