Recombinant Human Tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), partial (Active), Homo sapiens (Human), Mammalian cell, C-terminal hFc1-Flag-tagged, 36.4 kDa, purity >95% as determined by SDS-PAGE.
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Recombinant Human Tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), partial (Active)

Recombinant Human Tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), partial (Active) — B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Purity >95%.

SKU: BCACP-000098 Categories: ,
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Product SKUBCACP-000098
Product DescriptionRecombinant Human Tumor necrosis factor receptor superfamily member 13C (TNFRSF13C) protein is expressed from Mammalian cell with C-terminal hFc1-Flag-tagged. It contains 7-71aa. [Accession | Q96RJ3].
Uniprot No.Q96RJ3
Gene NamesTNFRSF13C
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region7-71aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal hFc1-Flag-tagged
Molecular weight36.4 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Anti-CD44 Mouse Monoclonal Antibody at 2 μg/ml can bind Biotinylated human CD44, the EC50 is 2.865-5.099 ng/ml.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative Names(B-cell-activating factor receptor)(BAFF receptor)(BAFF-R)(BLyS receptor 3)(CD268)(BAFFR)(BR3)

Function

B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response.

Biological Context

Subcellular Location: Membrane (Single-pass type III membrane protein)
Tissue Specificity: Highly expressed in spleen and lymph node, and in resting B-cells. Detected at lower levels in activated B-cells, resting CD4+ T-cells, in thymus and peripheral blood leukocytes
Disease Association: Immunodeficiency, common variable, 4 (CVID4) : A primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 7-71aa, with C-terminal hFc1-Flag-tagged tag, molecular weight 36.4 kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response

Subcellular Location

Membrane (Single-pass type III membrane protein)

Disease Association

Immunodeficiency, common variable, 4 (CVID4) : A primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low. [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

Highly expressed in spleen and lymph node, and in resting B-cells. Detected at lower levels in activated B-cells, resting CD4+ T-cells, in thymus and peripheral blood leukocytes

Gene: TNFRSF13C  |  Organism: Homo sapiens  |  Synonyms: B-cell-activating factor receptor; BAFF receptor; BLyS receptor 3
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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