Recombinant Human Tumor-associated calcium signal transducer 2 (TACSTD2), partial (Active), Homo sapiens (Human), Mammalian cell, C-terminal hFc1-tagged, 56.8 kDa, purity >90% as determined by SDS-PAGE.Greater than 95% as determined by SEC-HPLC.

Recombinant Human Tumor-associated calcium signal transducer 2 (TACSTD2), partial (Active)

Recombinant Human Tumor-associated calcium signal transducer 2 (TACSTD2), partial (Active) — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >90%.

SKU: BCACP-000003 Category:
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Product SKUBCACP-000003
Product DescriptionRecombinant Human Tumor-associated calcium signal transducer 2 (TACSTD2) protein is expressed from Mammalian cell with C-terminal hFc1-tagged. It contains 27-274aa. [Accession | P09758].
Uniprot No.P09758
Gene NamesTACSTD2
PurityGreater than 90% as determined by SDS-PAGE.Greater than 95% as determined by SEC-HPLC.
Expression SystemMammalian cell
Expression Region27-274aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal hFc1-tagged
Molecular weight56.8 kDa
ActivityMeasured in cell activity assay using U937 cells. The EC50 for this effect is 190.2-298.6 ng/ml.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesTACSTD2; GA733-1; M1S1; TROP2; Tumor-associated calcium signal transducer 2; Cell surface glycoprotein Trop-2; Membrane component chromosome 1 surface marker 1; Pancreatic carcinoma marker protein GA733-1

Function

May function as a growth factor receptor.

Biological Context

Subcellular Location: Membrane (Single-pass type I membrane protein)
Tissue Specificity: Placenta, pancreatic carcinoma cell lines
Disease Association: Corneal dystrophy, gelatinous drop-like (GDLD) : A form of lattice corneal dystrophy, a class of inherited stromal amyloidoses characterized by pathognomonic branching lattice figures in the cornea. GDLD is an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness. Clinical manifestations, which appear in the first decade of life, include blurred vision, photophobia, and foreign-body sensation. By the third decade, raised, yellowish-gray, gelatinous masses severely impair visual acuity. [The disease is caused by variants affecting the gene represented in this entry]

Product Specifications

Recombinant Human Tumor-associated calcium signal transducer 2 (TACSTD2), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 27-274aa, with C-terminal hFc1-tagged tag, molecular weight 56.8 kDa, purity Greater than 90% as determined by SDS-PAGE.Greater than 95% as determined by SEC-HPLC.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured in cell activity assay using U937 cells. The EC50 for this effect is 190.2-298.6 ng/ml.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

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Protein Biology

Function

May function as a growth factor receptor

Subcellular Location

Membrane (Single-pass type I membrane protein)

Disease Association

Corneal dystrophy, gelatinous drop-like (GDLD) : A form of lattice corneal dystrophy, a class of inherited stromal amyloidoses characterized by pathognomonic branching lattice figures in the cornea. GDLD is an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness. Clinical manifestations, which appear in the first decade of life, include blurred vision, photophobia, and foreign-body sensation. By the third decade, raised, yellowish-gray, gelatinous masses severely impair visual acuity. [The disease is caused by variants affecting the gene represented in this entry]

Tissue Specificity

Placenta, pancreatic carcinoma cell lines

Gene: TACSTD2  |  Organism: Homo sapiens  |  Synonyms: Cell surface glycoprotein Trop-2; Membrane component chromosome 1 surface marker 1; Pancreatic carcinoma marker protein GA733-1
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How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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