Recombinant Human Mucin-17 (MUC17), partial (Active), Homo sapiens (Human), Mammalian cell, C-terminal 10xHis-tagged, 32.0kDa, purity >95% as determined by SDS-PAGE.

Recombinant Human Mucin-17 (MUC17), partial (Active)

Recombinant Human Mucin-17 (MUC17), partial (Active) — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >95%.

SKU: BCACP-000210 Category:
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Product SKUBCACP-000210
Product DescriptionRecombinant Human Mucin-17 (MUC17) protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 4131-4390aa. [Accession | Q685J3].
Uniprot No.Q685J3
Gene NamesMUC17
PurityGreater than 95% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region4131-4390aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 10xHis-tagged
Molecular weight32.0kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Human TPBG at 2 μg/mL can bind Anti-TPBG recombinant antibody , the EC50 is 1.230-1.519 ng/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative Names(MUC-17)(Small intestinal mucin-3)(MUC-3)

Function

Probably plays a role in maintaining homeostasis on mucosal surfaces.

Biological Context

Subcellular Location: Secreted; Cell membrane
Tissue Specificity: Expressed almost exclusively in the intestine. Expression is especially high in both the duodenum and transverse colon. Expressed in mature absorptive cells of the small intestinal villi. No expression is detected in goblet cells. Highly expressed in pancreatic adenocarcinoma tissue (at protein level). Expression is not detectable in normal pancreas, in pancreatitis or in cell lines derived from other cancers

Product Specifications

Recombinant Human Mucin-17 (MUC17), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 4131-4390aa, with C-terminal 10xHis-tagged tag, molecular weight 32.0kDa, purity Greater than 95% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Catalog number: BCACP-000210.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Probably plays a role in maintaining homeostasis on mucosal surfaces

Subcellular Location

Secreted; Cell membrane

Tissue Specificity

Expressed almost exclusively in the intestine. Expression is especially high in both the duodenum and transverse colon. Expressed in mature absorptive cells of the small intestinal villi. No expression is detected in goblet cells. Highly expressed in pancreatic adenocarcinoma tissue (at protein level). Expression is not detectable in normal pancreas, in pancreatitis or in cell lines derived from other cancers

Subunit

Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization

Gene: MUC17  |  Organism: Homo sapiens  |  Synonyms: Small intestinal mucin-3
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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