Recombinant Rat Tumor necrosis factor receptor superfamily member 1A (Tnfrsf1a), partial (Active), Rattus norvegicus (Rat), Mammalian cell, C-terminal hFc1-tagged, 49.0 kDa, purity >90% as determined by SDS-PAGE.
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Recombinant Rat Tumor necrosis factor receptor superfamily member 1A (Tnfrsf1a), partial (Active)

Recombinant Rat Tumor necrosis factor receptor superfamily member 1A (Tnfrsf1a), partial (Active) — Receptor for TNFSF2/TNF and homotrimeric TNFSF1/lymphotoxin-alpha. Purity >90%.

SKU: BCACP-000600 Categories: ,
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Product SKUBCACP-000600
Product DescriptionRecombinant Rat Tumor necrosis factor receptor superfamily member 1A (Tnfrsf1a) protein is expressed from Mammalian cell with C-terminal hFc1-tagged. It contains 30-211aa. [Accession | P22934].
Uniprot No.P22934
Gene NamesTnfrsf1a
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region30-211aa
SpeciesRattus norvegicus (Rat)
Tag InfoC-terminal hFc1-tagged
Molecular weight49.0 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Human IL21R at 2 μg/mL can bind Human IL21 . The EC50 is 16.65-19.49 ng/mL.;Human IL21 captured on Protein A Chip can bind Recombinant Human IL21R with an affinity constant of 1.87 nM as detected by MetaSPR Assay (WeSPRTM 200).
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesTumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor 1; TNF-R1; Tumor necrosis factor receptor type I; TNF-RI; TNFR-I; p55; p60; CD antigen CD120a

Function

Receptor for TNFSF2/TNF and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.

Product Specifications

Recombinant Rat Tumor necrosis factor receptor superfamily member 1A (Tnfrsf1a), partial (Active) is a recombinant protein, expressed in Mammalian cell, covering amino acids 30-211aa, with C-terminal hFc1-tagged tag, molecular weight 49.0 kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

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Protein Biology

Function

Receptor for TNFSF2/TNF and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis (By similarity)

Gene: Tnfrsf1a  |  Organism: Rattus norvegicus

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

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