Recombinant Human Asialoglycoprotein receptor 1 (ASGR1)-Detergent (Active), Homo sapiens (Human), Mammalian cell, C-terminal 10xHis-tagged, 34.6 kDa, purity >85% as determined by SDS-PAGE.

Recombinant Human Asialoglycoprotein receptor 1 (ASGR1)-Detergent (Active)

Recombinant Human Asialoglycoprotein receptor 1 (ASGR1)-Detergent (Active) — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >85%.

SKU: BCACP-000619 Category:
Online Inquiry →
Product SKUBCACP-000619
Product DescriptionRecombinant Human Asialoglycoprotein receptor 1 (ASGR1)-Detergent protein is expressed from Mammalian cell with C-terminal 10xHis-tagged. It contains 1-291aa. [Accession | P07306].
Uniprot No.P07306
Gene NamesASGR1
PurityGreater than 85% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region1-291aa
SpeciesHomo sapiens (Human)
Tag InfoC-terminal 10xHis-tagged
Molecular weight34.6 kDa
ActivityMeasured by its binding ability in a functional ELISA. Immobilized Mouse Tnfsf4 at 4 μg/mL can bind Mouse Tnfrsf4. The EC50 is 3.581-4.060 ng/mL.;Mouse Tnfrsf4 captured on Protein A Chip can bind Recombinant Mouse Tnfsf4 with an affinity constant of 0.438 nM as detected by MetaSPR Assay (WeSPRTM 200).
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesAsialoglycoprotein receptor 1; ASGP-R 1; ASGPR 1; C-type lectin domain family 4 member H1; Hepatic lectin H1; HL-1

Function

(Microbial infection) Plays an essential role in ACE2-independent SARS-CoV-2 entry by acting as alternate receptor.

Biological Context

Subcellular Location: Secreted
Tissue Specificity: Expressed exclusively in hepatic parenchymal cells

Product Specifications

Recombinant Human Asialoglycoprotein receptor 1 (ASGR1)-Detergent (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 1-291aa, with C-terminal 10xHis-tagged tag, molecular weight 34.6 kDa, purity Greater than 85% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

SDS-PAGE: Single band at expected molecular weight confirming purity.

ELISA: Suitable as coating antigen or detection standard.

Western Blot: Compatible with standard Western Blot protocols.

Protein Interaction: Validated for SPR (Surface Plasmon Resonance) and BLI (Bio-Layer Interferometry) studies.

Shipping: Shipped at ambient temperature. Lyophilized protein is stable during transit.

Storage: Store lyophilized protein at -20°C to -80°C. Reconstituted protein should be aliquoted and stored at -80°C. Avoid repeated freeze-thaw cycles.

Shelf Life: 12 months from date of receipt when stored as recommended.

Shipping Time: Orders placed before 2 PM EST ship same day. International orders typically deliver within 5-10 business days.

Related products

Protein Biology

Function

(Microbial infection) Plays an essential role in ACE2-independent SARS-CoV-2 entry by acting as alternate receptor

Subcellular Location

Secreted

Tissue Specificity

Expressed exclusively in hepatic parenchymal cells

Subunit

(Microbial infection) Interacts with SARS-CoV-2 virus spike glycoprotein

Gene: ASGR1  |  Organism: Homo sapiens  |  Synonyms: C-type lectin domain family 4 member H1; Hepatic lectin H1
Key Publications

Frequently Asked Questions

How do I order or inquire about this product?

Fill out the Online Inquiry form with your required quantity and specifications. You can also email sales@biocrestsci.com. Our team typically responds within 4 business hours with a quote and availability confirmation.

What is the shipping and delivery time?

Orders placed before 2 PM EST ship the same day. Domestic (US) delivery typically takes 2-3 business days. International orders deliver within 5-10 business days. All products are shipped at ambient temperature with appropriate packaging to ensure stability.

How should I store this recombinant protein?

Lyophilized proteins should be stored at -20°C to -80°C upon receipt. After reconstitution, aliquot and store at -80°C. Avoid repeated freeze-thaw cycles. Shelf life is 12 months from date of receipt when stored as recommended.

What quality controls are performed on your products?

Each product undergoes SDS-PAGE purity analysis (typically >85-95%), endotoxin testing, and bioactivity validation. Products are validated for ELISA, Western Blot, and SPR/BLI applications as specified on this product page. A Certificate of Analysis (CoA) is available upon request.

Shopping Cart
Scroll to Top