Recombinant Human Sialic acid-binding Ig-like lectin 15 (SIGLEC15), partial (Active)

Recombinant Human Sialic acid-binding Ig-like lectin 15 (SIGLEC15), partial (Active) — recombinant protein from Homo sapiens (Human), expressed in Mammalian cell. Purity >90%.

SKU: BCACP-000023 Category:
Product SKUBCACP-000023
Product DescriptionRecombinant Human Sialic acid-binding Ig-like lectin 15 (SIGLEC15) protein is expressed from Mammalian cell with N-terminal 6xHis-Myc-tagged. It contains 20-263aa. [Accession | Q6ZMC9].
Uniprot No.Q6ZMC9
Gene NamesSIGLEC15
PurityGreater than 90% as determined by SDS-PAGE.
Expression SystemMammalian cell
Expression Region20-263aa
SpeciesHomo sapiens (Human)
Tag InfoN-terminal 6xHis-Myc-tagged
Molecular weight30.7 kDa
ActivityMeasured by its binding ability in a functional ELISA.Immobilized Human SIGLEC15 at 5 μg/mL can bind Anti-SIGLEC15 recombinant antibody. The EC50 is 12.42-16.08 ng/mL.
BufferLyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
StorageStore at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Alternative NamesSialic acid-binding Ig-like lectin 15; Siglec-15; CD33 antigen-like 3; SIGLEC15; CD33L3

Function

Binds sialylated glycoproteins.

Biological Context

Subcellular Location: Membrane (Single-pass type I membrane protein)
Tissue Specificity: Expressed in macrophage and/or dendritic cells of spleen and lymph nodes

Product Specifications

Recombinant Human Sialic acid-binding Ig-like lectin 15 (SIGLEC15), partial (Active) is a recombinant protein from Homo sapiens (Human), expressed in Mammalian cell, covering amino acids 20-263aa, with N-terminal 6xHis-Myc-tagged tag, molecular weight 30.7 kDa, purity Greater than 90% as determined by SDS-PAGE.. Suitable for ELISA and Western Blot applications.

Recommended applications depend on the target, product format, and product-specific validation data. Refer to the product datasheet or Certificate of Analysis (CoA), or contact BioCrest Sci for application guidance.

Biological Activity: Measured by its binding ability in a functional ELISA.Immobilized Human SIGLEC15 at 5 μg/mL can bind Anti-SIGLEC15 recombinant antibody. The EC50 is 12.42-16.08 ng/mL.

Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shipping & Lead Time: Availability, shipping conditions, and estimated lead time are confirmed in the formal quotation or order confirmation based on the product format, destination, and order requirements.

Protein Biology

Function

Binds sialylated glycoproteins

Subcellular Location

Membrane (Single-pass type I membrane protein)

Tissue Specificity

Expressed in macrophage and/or dendritic cells of spleen and lymph nodes

Subunit

Interacts with TYROBP and HCST

Gene: SIGLEC15  |  Organism: Homo sapiens  |  Synonyms: CD33 antigen-like 3

Frequently Asked Questions

How do I order or inquire about this product?

Submit the Online Inquiry form with your required quantity and specifications, or email sales@biocrestsci.com. Available sizes, pricing, stock status, documentation, and estimated lead time are confirmed in the formal quotation.

What is the shipping and delivery time?

Availability, dispatch timing, shipping conditions, and delivery estimates depend on the product format, destination, and order requirements. These details are confirmed in the formal quotation or order confirmation.

How should this product be stored?

Follow the storage and handling instructions in the product-specific datasheet and Certificate of Analysis (CoA). Requirements may vary by product form and formulation; contact BioCrest Sci if product-specific guidance is needed.

What quality controls are performed on your products?

Quality-control data such as identity, purity, endotoxin level, or biological activity are provided only when specified on this product page, the datasheet, or Certificate of Analysis (CoA). Biological activity is not implied unless explicitly stated.

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